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Study · Non-randomized trial · n = 7 · 1986

1 result

Somatostatin inhibits the dermorphin-stimulated thyrotropin release in man.

degli Uberti EC, Roti E, Trasforini G, Salvadori S, Margutti A, Robuschi G, Tomatis R, Gnudi A, Pansini R, Braverman LE

Hormone research1 Jan 1986Cited by 3 (Europe PMC)

PMID2870974 (opens in a new tab)DOI10.1159/000180325 (opens in a new tab)PepBankPUB-02870974
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In healthy men, intravenous dermorphin significantly increased serum thyrotropin concentration.

    In plain wordsIn healthy men, dermorphin increased blood thyrotropin levels.

    Peptide
    Dermorphin
    Outcome
    IncreaseSerum thyrotropin concentration
    Study

    n = 7

    Outcome group
    Thyroid function · Endocrine and hormones
    Studied dose
    Dose not stated · intravenousAs given in this study (human).

    Source sentences

    Summary
    D significantly increased the serum TSH concentration.
    1 context sentence
    Summary · context
    We have studied the effect of the intravenous administration of somatostatin (SRIF) on the thyrotropin (TSH) response to intravenous dermorphin (D), a new potent opioid peptide, in 7 healthy men.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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