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Study · In vitro (cells) · rat · 1985

2 results

The effects of growth hormone, prolactin, corticotropin, and thyrotropin on the production and secretion of somatostatin by hypothalamic cells in vitro.

Robbins RJ, Leidy JW Jr, Landon RM

Endocrinology1 Aug 1985Cited by 15 (Europe PMC)

PMID2862010 (opens in a new tab)DOI10.1210/endo-117-2-538 (opens in a new tab)PepBankPUB-02862010
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In cultured rat hypothalamic cells, cosyntropin inhibited immunoreactive somatostatin release.

    In plain wordsIn cells from rat embryos, cosyntropin reduced somatostatin release.

    Peptide
    Cosyntropin
    Outcome
    DecreaseSomatostatin release
    Study

    ratn: not reported in source

    Cultured embryonic hypothalamic cells
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Cosyntropin, an ACTH analog, inhibited both IRS release and cell content
    1 context sentence
    Summary · context
    Hypothalamic cells prepared from 17-day-old rat embryos and maintained as reaggregate monolayers for 12 days in vitro were used.
  2. 02LabIn vitro (cells)Mechanism

    In cultured rat hypothalamic cells, cosyntropin inhibited cellular immunoreactive somatostatin content.

    In plain wordsIn cells from rat embryos, cosyntropin reduced somatostatin content.

    Peptide
    Cosyntropin
    Outcome
    DecreaseCellular somatostatin content
    Study

    ratn: not reported in source

    Cultured embryonic hypothalamic cells
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Cosyntropin, an ACTH analog, inhibited both IRS release and cell content
    1 context sentence
    Summary · context
    Hypothalamic cells prepared from 17-day-old rat embryos and maintained as reaggregate monolayers for 12 days in vitro were used.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:37 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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