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Study · Animal study (in vivo) · rat · 1985

2 results

Iontophoretic application of angiotensin II, vasopressin and oxytocin in the region of the anterior hypothalamus in the rat.

Thornton SN, Jeulin A, de Beaurepaire R, Nicolaidis S

Brain research bulletin1 Mar 1985Cited by 17 (Europe PMC)

PMID2859916 (opens in a new tab)DOI10.1016/0361-9230(85)90084-x (opens in a new tab)PepBankPUB-02859916
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In anaesthetized rats, 6 of 47 glutamate-responsive anterior hypothalamic cells increased firing to iontophoretic oxytocin.

    In plain wordsIn rats, 6 of 47 tested brain cells in the anterior hypothalamus fired more when oxytocin was applied.

    Peptide
    Oxytocin
    Outcome
    IncreaseAnterior hypothalamic cells increasing firing to oxytocin
    Study

    ratn: not reported in source

    Anaesthetized rats, single-cell recording
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated · iontophoreticAs given in this study (rat).

    Measurements

    Cells increasing firing to oxytocin
    6 cells
    47 glutamate-responsive cells

    Source sentences

    Summary
    Of the 47 cells found to responsive to Io glutamate, 23 increased firing to AII, 18 to AVP and 6 to Ox.
    2 context sentences
    Summary · context
    Using anaesthetized rats, we have looked at the activity of cells in this region through using a recording electrode cemented to a 7 barrelled iontophoretic electrode inserted ventrally.
    Summary · context
    Cells were tested for their responsiveness to iontophoretic application (Io) of angiotensin II (AII), vasopressin (AVP) and oxytocin (Ox).
  2. 02AnimalAnimal study (in vivo)Activity measurement

    In anaesthetized rats, two anterior hypothalamic cells responded to both oxytocin and angiotensin II.

    In plain wordsIn rats, two brain cells in the anterior hypothalamus responded to both oxytocin and angiotensin II.

    Peptide
    Oxytocin
    Outcome
    Not applicableCells responding to both oxytocin and angiotensin II
    Study

    ratn: not reported in source

    Anaesthetized rats, single-cell recording
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated · iontophoreticAs given in this study (rat).

    Source sentences

    Summary
    Two cells responded to both Ox and AII.
    2 context sentences
    Summary · context
    Using anaesthetized rats, we have looked at the activity of cells in this region through using a recording electrode cemented to a 7 barrelled iontophoretic electrode inserted ventrally.
    Summary · context
    Cells were tested for their responsiveness to iontophoretic application (Io) of angiotensin II (AII), vasopressin (AVP) and oxytocin (Ox).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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