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Study · Measured the body's own peptide · 1985

5 results

Delta-sleep inducing peptide in cerebrospinal fluid from schizophrenics, depressives and healthy volunteers.

Lindström LH, Ekman R, Walleus H, Widerlöv E

Progress in neuro-psychopharmacology & biological psychiatry1 Jan 1985Cited by 15 (Europe PMC)

PMID2859636 (opens in a new tab)DOI10.1016/0278-5846(85)90182-4 (opens in a new tab)PepBankPUB-02859636
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In hospitalized adults with schizophrenia, CSF DSIP levels were significantly lower than in healthy volunteers.

    In plain wordsIn adults with schizophrenia, the body's own DSIP level in spinal fluid was lower than in healthy volunteers.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseCSF DSIP level in schizophrenia versus healthy volunteers
    Study

    n: not reported in source

    Comparator
    Healthy volunteers
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Both patient groups had significantly lower CSF levels of DSIP than the healthy volunteers.
    1 context sentence
    Summary · context
    CSF levels of DSIP was measured in healthy volunteers and in hospitalized patients with schizophrenia or major depressive disorders.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In hospitalized adults with major depressive disorder, CSF DSIP levels were significantly lower than in healthy volunteers.

    In plain wordsIn adults with major depression, the body's own DSIP level in spinal fluid was lower than in healthy volunteers.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseCSF DSIP level in major depression versus healthy volunteers
    Study

    n: not reported in source

    Comparator
    Healthy volunteers
    Outcome group
    Endogenous peptide levels · Mental health and mood

    Source sentences

    Summary
    Both patient groups had significantly lower CSF levels of DSIP than the healthy volunteers.
    1 context sentence
    Summary · context
    CSF levels of DSIP was measured in healthy volunteers and in hospitalized patients with schizophrenia or major depressive disorders.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In patients with schizophrenia, CSF DSIP levels tended to be lower in women than in men; the abstract reports a tendency only.

    In plain wordsIn people with schizophrenia, the body's own DSIP level in spinal fluid tended to be lower in women than in men.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeCSF DSIP level, female versus male schizophrenics
    Study

    n: not reported in source

    Comparator
    Male patients with schizophrenia
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    There was a tendency for lower CSF levels of DSIP in female compared to male schizophrenics.
    1 context sentence
    Summary · context
    CSF levels of DSIP was measured in healthy volunteers and in hospitalized patients with schizophrenia or major depressive disorders.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  4. 04HumanEndogenous levelObservational studyOther

    In patients with schizophrenia or depression, neuroleptic treatment did not significantly change CSF DSIP levels.

    In plain wordsIn patients, neuroleptic drugs did not significantly change the body's own DSIP level in spinal fluid.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeEffect of neuroleptic treatment on CSF DSIP level
    Study

    n: not reported in source

    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Neuroleptic treatment did not significantly affect those levels.
    1 context sentence
    Summary · context
    CSF levels of DSIP was measured in healthy volunteers and in hospitalized patients with schizophrenia or major depressive disorders.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  5. 05HumanEndogenous levelObservational studyOther

    In depressed patients, CSF DSIP levels tended to be inversely correlated with sleep disturbance scores; the abstract reports a tendency only.

    In plain wordsIn depressed patients, lower natural DSIP levels in spinal fluid tended to go with more sleep problems.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeCorrelation of CSF DSIP with sleep disturbance score in depression
    Study

    n: not reported in source

    Outcome group
    Sleep · Sleep

    Source sentences

    Summary
    The levels of DSIP in CSF tended to be inversely correlated to the sleep disturbancy scores in the depressed patients.
    1 context sentence
    Summary · context
    CSF levels of DSIP was measured in healthy volunteers and in hospitalized patients with schizophrenia or major depressive disorders.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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