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Study · In vitro (cells) · mouse · 1988

1 result

Osteoblastic cells are involved in osteoclast formation.

Takahashi N, Akatsu T, Udagawa N, Sasaki T, Yamaguchi A, Moseley JM, Martin TJ, Suda T

Endocrinology1 Nov 1988Cited by 646 (Europe PMC)

PMID2844518 (opens in a new tab)DOI10.1210/endo-123-5-2600 (opens in a new tab)PepBankPUB-02844518
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In vitamin D-treated mouse spleen cell and osteoblast co-cultures, salmon calcitonin markedly increased cAMP production.

    In plain wordsIn mouse cell co-cultures treated with vitamin D, salmon calcitonin increased cAMP production.

    Peptide
    Calcitonin-salmon
    Outcome
    IncreasecAMP production
    Study

    mousen: not reported in source

    Mouse spleen cell and osteoblast co-cultures
    Outcome group
    Receptor activity and mechanism · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Salmon calcitonin (CT) markedly increased cAMP production in the co-cultures treated with 1 alpha,25(OH)2D3.
    1 context sentence
    Summary · context
    We developed a co-culture system with mouse spleen cells and osteoblastic cells to examine the role of osteoblasts in osteoclast formation.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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