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Study · Animal study (in vivo) · cat · 1989

3 results

[Effects of delta sleep-inducing peptide on the intercentral integration during experimental epilepsy].

Popova NS, Adrianov OS, Veskov R, Iankovich B, Rakich L

Biulleten' eksperimental'noi biologii i meditsiny1 Aug 1989Cited by 1 (Europe PMC)

PMID2804316 (opens in a new tab)PepBankPUB-02804316
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In cats with experimental epilepsy, DSIP may change the organization of the pathology integration, so that epileptic discharges did not spread to all structures simultaneously.

    In plain wordsIn cats with experimental epilepsy, DSIP may change how seizure activity spreads in the brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    MixedOrganization of epileptic discharge integration
    Study

    catn: not reported in source

    experimental epilepsy, free behavior
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    100 mg/kg · intraperitonealAs given in this study (cat).

    Source sentences

    Summary
    may change organization of the pathology integration-epileptic discharges did not spread all the structures simultaneously
    1 context sentence
    Summary · context
    In free behavior experiments on cats it has been shown, that the intraperitoneal injection of delta-sleep-inducing peptide (100 mg/kg) may change organization of the pathology integration-epileptic discharges did not spread all the structures simultaneously.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In cats with experimental epilepsy given DSIP, slow waves were registered in the central medium of the thalamus and in the caudate nuclei.

    In plain wordsIn cats with experimental epilepsy given DSIP, slow brain waves were recorded in the thalamus and the caudate nuclei.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableSlow waves in thalamus and caudate nuclei
    Study

    catn: not reported in source

    experimental epilepsy, free behavior
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    100 mg/kg · intraperitonealAs given in this study (cat).

    Source sentences

    Summary
    The slow-waves were registered in central medium of the thalamus and nucl. caudati.
    1 context sentence
    Summary · context
    In free behavior experiments on cats it has been shown, that the intraperitoneal injection of delta-sleep-inducing peptide (100 mg/kg) may change organization of the pathology integration-epileptic discharges did not spread all the structures simultaneously.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In cats with experimental epilepsy given DSIP, discharges appeared first in visual and auditory cortex and hippocampus, then in motor cortex, caudate nuclei and thalamic centrum medianum.

    In plain wordsIn cats with experimental epilepsy given DSIP, seizure discharges started in sensory brain areas and then reached movement areas.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableSequence of epileptic discharge spread
    Study

    catn: not reported in source

    experimental epilepsy, free behavior
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    100 mg/kg · intraperitonealAs given in this study (cat).

    Source sentences

    Summary
    The epileptic discharges were registered first in visual and auditory cortex, hippocampus. After that they were observed in the motor cortex, nucl. caudati and centrum medianum of the thalamus.
    1 context sentence
    Summary · context
    In free behavior experiments on cats it has been shown, that the intraperitoneal injection of delta-sleep-inducing peptide (100 mg/kg) may change organization of the pathology integration-epileptic discharges did not spread all the structures simultaneously.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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