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Study · Ex vivo tissue · mouse · 1989

8 results

Thymic hormones and prostaglandins. I. Lack of stimulation of prostaglandin production by thymic hormones.

Homo-Delarche F, Bach JF, Dardenne M

Prostaglandins1 Aug 1989Cited by 4 (Europe PMC)

PMID2788896 (opens in a new tab)DOI10.1016/0090-6980(89)90081-6 (opens in a new tab)PepBankPUB-02788896
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

8 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueMechanism

    In spleen cells from control and thymectomized mice, thymosin alpha‑1 did not affect PGE2 production.

    In plain wordsIn lab tests with mouse spleen cells, thymosin alpha‑1 did not change PGE2 production.

    Peptide
    Thymosin alpha-1
    Outcome
    No significant changePGE2 production by spleen cells
    Study

    mousen: not reported in source

    spleen cells from control and thymectomized mice
    Outcome group
    Inflammation markers · Immune and inflammation
    Studied dose
    1-10 micrograms/ml · in vitroAs given in this study (mouse).

    Source sentences

    Summary
    Attempts to modulate prostaglandin production showed that neither thymosin fraction 5 (0.01-100 micrograms/ml), nor thymosin alpha 1 (1-10 micrograms/ml), thymulin (0.001-100 ng/ml), thymopoietin II (10-1000 ng/ml) or TP5 (10-1000 ng/ml) affect PGE2, 6-keto-PGF1 alpha, PGF2 alpha and TXB2 production…
  2. 02LabEx vivo tissueMechanism

    In spleen cells from control and thymectomized mice, thymosin alpha‑1 did not affect 6-keto-PGF1 alpha production.

    In plain wordsIn lab tests with mouse spleen cells, thymosin alpha‑1 did not change 6-keto-PGF1 alpha production.

    Peptide
    Thymosin alpha-1
    Outcome
    No significant change6-keto-PGF1 alpha production by spleen cells
    Study

    mousen: not reported in source

    spleen cells from control and thymectomized mice
    Outcome group
    Inflammation markers · Immune and inflammation
    Studied dose
    1-10 micrograms/ml · in vitroAs given in this study (mouse).

    Source sentences

    Summary
    Attempts to modulate prostaglandin production showed that neither thymosin fraction 5 (0.01-100 micrograms/ml), nor thymosin alpha 1 (1-10 micrograms/ml), thymulin (0.001-100 ng/ml), thymopoietin II (10-1000 ng/ml) or TP5 (10-1000 ng/ml) affect PGE2, 6-keto-PGF1 alpha, PGF2 alpha and TXB2 production…
  3. 03LabEx vivo tissueMechanism

    In spleen cells from control and thymectomized mice, thymosin alpha‑1 did not affect PGF2 alpha production.

    In plain wordsIn lab tests with mouse spleen cells, thymosin alpha‑1 did not change PGF2 alpha production.

    Peptide
    Thymosin alpha-1
    Outcome
    No significant changePGF2 alpha production by spleen cells
    Study

    mousen: not reported in source

    spleen cells from control and thymectomized mice
    Outcome group
    Inflammation markers · Immune and inflammation
    Studied dose
    1-10 micrograms/ml · in vitroAs given in this study (mouse).

    Source sentences

    Summary
    Attempts to modulate prostaglandin production showed that neither thymosin fraction 5 (0.01-100 micrograms/ml), nor thymosin alpha 1 (1-10 micrograms/ml), thymulin (0.001-100 ng/ml), thymopoietin II (10-1000 ng/ml) or TP5 (10-1000 ng/ml) affect PGE2, 6-keto-PGF1 alpha, PGF2 alpha and TXB2 production…
  4. 04LabEx vivo tissueMechanism

    In spleen cells from control and thymectomized mice, thymosin alpha‑1 did not affect TXB2 production.

    In plain wordsIn lab tests with mouse spleen cells, thymosin alpha‑1 did not change TXB2 production.

    Peptide
    Thymosin alpha-1
    Outcome
    No significant changeTXB2 production by spleen cells
    Study

    mousen: not reported in source

    spleen cells from control and thymectomized mice
    Outcome group
    Inflammation markers · Immune and inflammation
    Studied dose
    1-10 micrograms/ml · in vitroAs given in this study (mouse).

    Source sentences

    Summary
    Attempts to modulate prostaglandin production showed that neither thymosin fraction 5 (0.01-100 micrograms/ml), nor thymosin alpha 1 (1-10 micrograms/ml), thymulin (0.001-100 ng/ml), thymopoietin II (10-1000 ng/ml) or TP5 (10-1000 ng/ml) affect PGE2, 6-keto-PGF1 alpha, PGF2 alpha and TXB2 production…
  5. 05LabIn vitro (cells)Mechanism

    In spleen cells from control and thymectomized mice, thymulin did not affect PGE2 production.

    In plain wordsIn lab tests with mouse spleen cells, thymulin did not change PGE2 production.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changePGE2 production
    Study

    mousen: not reported in source

    Spleen cells from control and thymectomized mice
    Outcome group
    Receptor activity and mechanism · Immune and inflammation
    Studied dose
    0.001-100 ng/mlAs given in this study (mouse).

    Source sentences

    Summary
    Attempts to modulate prostaglandin production showed that neither thymosin fraction 5 (0.01-100 micrograms/ml), nor thymosin alpha 1 (1-10 micrograms/ml), thymulin (0.001-100 ng/ml), thymopoietin II (10-1000 ng/ml) or TP5 (10-1000 ng/ml) affect PGE2, 6-keto-PGF1 alpha, PGF2 alpha and TXB2 production…
  6. 06LabIn vitro (cells)Mechanism

    In spleen cells from control and thymectomized mice, thymulin did not affect 6-keto-PGF1 alpha production.

    In plain wordsIn lab tests with mouse spleen cells, thymulin did not change 6-keto-PGF1 alpha production.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant change6-keto-PGF1 alpha production
    Study

    mousen: not reported in source

    Spleen cells from control and thymectomized mice
    Outcome group
    Receptor activity and mechanism · Immune and inflammation
    Studied dose
    0.001-100 ng/mlAs given in this study (mouse).

    Source sentences

    Summary
    Attempts to modulate prostaglandin production showed that neither thymosin fraction 5 (0.01-100 micrograms/ml), nor thymosin alpha 1 (1-10 micrograms/ml), thymulin (0.001-100 ng/ml), thymopoietin II (10-1000 ng/ml) or TP5 (10-1000 ng/ml) affect PGE2, 6-keto-PGF1 alpha, PGF2 alpha and TXB2 production…
  7. 07LabIn vitro (cells)Mechanism

    In spleen cells from control and thymectomized mice, thymulin did not affect PGF2 alpha production.

    In plain wordsIn lab tests with mouse spleen cells, thymulin did not change PGF2 alpha production.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changePGF2 alpha production
    Study

    mousen: not reported in source

    Spleen cells from control and thymectomized mice
    Outcome group
    Receptor activity and mechanism · Immune and inflammation
    Studied dose
    0.001-100 ng/mlAs given in this study (mouse).

    Source sentences

    Summary
    Attempts to modulate prostaglandin production showed that neither thymosin fraction 5 (0.01-100 micrograms/ml), nor thymosin alpha 1 (1-10 micrograms/ml), thymulin (0.001-100 ng/ml), thymopoietin II (10-1000 ng/ml) or TP5 (10-1000 ng/ml) affect PGE2, 6-keto-PGF1 alpha, PGF2 alpha and TXB2 production…
  8. 08LabIn vitro (cells)Mechanism

    In spleen cells from control and thymectomized mice, thymulin did not affect TXB2 production.

    In plain wordsIn lab tests with mouse spleen cells, thymulin did not change TXB2 production.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeTXB2 production
    Study

    mousen: not reported in source

    Spleen cells from control and thymectomized mice
    Outcome group
    Receptor activity and mechanism · Immune and inflammation
    Studied dose
    0.001-100 ng/mlAs given in this study (mouse).

    Source sentences

    Summary
    Attempts to modulate prostaglandin production showed that neither thymosin fraction 5 (0.01-100 micrograms/ml), nor thymosin alpha 1 (1-10 micrograms/ml), thymulin (0.001-100 ng/ml), thymopoietin II (10-1000 ng/ml) or TP5 (10-1000 ng/ml) affect PGE2, 6-keto-PGF1 alpha, PGF2 alpha and TXB2 production…

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Versions 6 to 14Current

    28 Oct 2026, 02:02 UTC

    The same notice was added 9 times, first on 21 Oct 2026, 15:59 UTC. The status did not change between them.

    Study results updated

  2. Versions 4 to 5

    21 Oct 2026, 13:55 UTC

    The same notice was added 2 times, first on 21 Oct 2026, 12:50 UTC. The status did not change between them.

    Study data updated · source update from Europe PMC

  3. Version 3

    10 Oct 2026, 08:55 UTC

    Study results updated

  4. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  5. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

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