In cultured calf and rat thymocytes, large thymocytes produced prothymosin alpha, which contains the thymosin alpha‑1 sequence, in a higher concentration than small thymocytes.
In plain wordsIn lab cultures of calf and rat thymus cells, large cells made more of the thymosin alpha‑1 precursor than small cells.
- Peptide
- Thymosin alpha-1
- Outcome
- Not applicableProthymosin alpha synthesis by thymocyte subpopulations
- Study
calf, ratn: not reported in source
cultured thymocytes- Outcome group
- Immune response · Immune and inflammation
Source sentences
The polypeptide is produced in a major concentration by large thymocytes.
1 context sentence(design, population, supporting numbers)
Prothymosin alpha (ProT alpha), a polypeptide containing the sequence of thymosin alpha 1 (T alpha 1) at its NH2-terminus, has been isolated from calf thymocytes in a concentration in the order of that found in the whole thymic gland.
In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.