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Study · Animal study (in vivo) · rabbit · 1989

3 results

[Effect of delta-sleep inducing peptide on electrical instability of the heart in emotional stress].

Arkhangel'skaia MI, Zviagintseva MA

Patologicheskaia fiziologiia i eksperimental'naia terapiia1 Mar 1989

PMID2755725 (opens in a new tab)PepBankPUB-02755725
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rabbits under experimental emotional stress, DSIP diminished or arrested ventricular extrasystole.

    In plain wordsIn rabbits under stress, DSIP reduced or stopped extra heartbeats from the lower heart chambers.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseVentricular extrasystole in emotional stress
    Study

    rabbitn: not reported in source

    emotional stress
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    60 nmol/kgAs given in this study (rabbit).

    Source sentences

    Summary
    DSIP (60 nmol/kg) diminished or arrested ventricular extrasystole occurring in experimental emotional stress.
    1 context sentence
    Summary · context
    The effect of the delta-sleep inducing peptide (DSIP) on disorders of the cardiac rhythm in emotional stress was studied in experiments on rabbits.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rabbits, the antiarrhythmic effect of DSIP was most manifest when it was injected just before exposure to stress factors.

    In plain wordsIn rabbits, DSIP protected the heart rhythm best when injected just before stress.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseAntiarrhythmic effect by injection timing
    Study

    rabbitn: not reported in source

    emotional stress
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It was shown that the antiarrhythmic effect of DSIP is most manifest if it is injected just before exposure to the stress factors.
    1 context sentence
    Summary · context
    The effect of the delta-sleep inducing peptide (DSIP) on disorders of the cardiac rhythm in emotional stress was studied in experiments on rabbits.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In intact rabbits, DSIP injection increased the thresholds for ventricular fibrillation and its precursors.

    In plain wordsIn intact rabbits, DSIP injection raised the threshold for abnormal heart rhythms such as ventricular fibrillation.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseThresholds of ventricular fibrillation and its precursors in intact animals
    Study

    rabbitn: not reported in source

    emotional stress
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    DSIP injection induces increase of the thresholds of the occurrence of ventricular fibrillation and its precursors in intact animals.
    1 context sentence
    Summary · context
    The effect of the delta-sleep inducing peptide (DSIP) on disorders of the cardiac rhythm in emotional stress was studied in experiments on rabbits.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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