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Study · In vitro (cells) · mouse · 1989

1 result

The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells.

Udagawa N, Takahashi N, Akatsu T, Sasaki T, Yamaguchi A, Kodama H, Martin TJ, Suda T

Endocrinology1 Oct 1989Cited by 344 (Europe PMC)

PMID2676473 (opens in a new tab)DOI10.1210/endo-125-4-1805 (opens in a new tab)PepBankPUB-02676473
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In mouse cocultures, salmon calcitonin enhanced cAMP production only when TRACP-positive cells formed.

    In plain wordsIn mouse cells, salmon calcitonin increased cAMP production only when TRACP-positive cells formed.

    Peptide
    Calcitonin-salmon
    Outcome
    IncreasecAMP production
    Study

    mousen: not reported in source

    Mouse spleen and stromal cell cocultures
    Outcome group
    Receptor activity and mechanism · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Salmon calcitonin enhanced cAMP production in the cocultures only when TRACP-positive cells were formed.
    2 context sentences
    Summary · context
    We first used two clonal cell lines simultaneously established from newborn mouse calvariae.
    Summary · context
    One was the osteoblastic cell line MC3T3-E1, and the other was the preadipose cell line MC3T3-G2/PA6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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