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Study · Measured the body's own peptide · 1989

4 results

Delta sleep-inducing peptide (DSIP)-like immunoreactivity in gut: coexistence with known peptide hormones.

Bjartell A, Ekman R, Hedenbro J, Sjölund K, Sundler F

Peptides1 Jan 1989Cited by 8 (Europe PMC)

PMID2664725 (opens in a new tab)DOI10.1016/0196-9781(89)90093-4 (opens in a new tab)PepBankPUB-02664725
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueOther

    In human gut, DSIP-like immunoreactivity was located in gastrin/CCK, secretin and PYY/glicentin cells.

    In plain wordsIn human gut tissue, the body's own DSIP-like material was found in several hormone-producing cell types.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-LI in human gut endocrine cells
    Study

    humann: not reported in source

    Human gut tissue
    Outcome group
    Endogenous peptide levels · Gastrointestinal

    Source sentences

    Summary
    The human gut was the richest source, where DSIP-LI was located in gastrin/CCK, secretin and PYY/glicentin cells.
    1 context sentence
    Summary · context
    By means of three different antisera against synthetic DSIP we now describe the occurrence and distribution of DSIP-LI in several gut endocrine cells.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueOther

    Rat and pig gut had a moderate number of DSIP-immunoreactive cells in the antral mucosa and very few in the intestines.

    In plain wordsIn rats and pigs, few gut cells contained the body's own DSIP-like material, mostly in the stomach lining.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-LI cells in rat and pig gut
    Study

    rat, pign: not reported in source

    Rat and pig gut tissue
    Outcome group
    Endogenous peptide levels · Gastrointestinal

    Source sentences

    Summary
    The rat and pig gut harbour a moderate number of immunoreactive cells in the antral mucosa but in the intestines DSIP-LI-containing cells were very few.
    1 context sentence
    Summary · context
    By means of three different antisera against synthetic DSIP we now describe the occurrence and distribution of DSIP-LI in several gut endocrine cells.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelEx vivo tissueOther

    By radioimmunoassay, DSIP-like immunoreactivity concentrations in gut extracts were highest in all human specimens compared with pig and rat.

    In plain wordsHuman gut samples held more of the body's own DSIP-like material than pig and rat samples.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseDSIP-LI concentration in gut extracts across species
    Study

    human, pig, ratn: not reported in source

    Gut extracts
    Comparator
    Pig and rat samples
    Outcome group
    Endogenous peptide levels · Gastrointestinal

    Source sentences

    Summary
    By radioimmunoassay, the concentration of DSIP-LI was determined in extracts of various gut regions from man, pig and rat. The highest concentrations were found in all human specimens compared with corresponding samples in the pig and rat.
    1 context sentence
    Summary · context
    By means of three different antisera against synthetic DSIP we now describe the occurrence and distribution of DSIP-LI in several gut endocrine cells.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  4. 04LabEndogenous levelEx vivo tissueOther

    In extracts from human, pig and rat gut, high-performance liquid chromatography revealed a single peak of DSIP-like material with about the same retention time as DSIP 3-9.

    In plain wordsIn lab tests of gut extracts from three species, the body's own DSIP-like material appeared as one peak close to a DSIP fragment.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableHPLC profile of DSIP-like material
    Study

    human, pig, ratn: not reported in source

    Gut extracts
    Outcome group
    Endogenous peptide levels · Gastrointestinal

    Source sentences

    Summary
    In all three species, high-performance liquid chromatography revealed a single peak of DSIP-like material with approximately the same retention time as DSIP 3-9.
    1 context sentence
    Summary · context
    By means of three different antisera against synthetic DSIP we now describe the occurrence and distribution of DSIP-LI in several gut endocrine cells.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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