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Study · Measured the body's own peptide · 1989

8 results

Immunohistochemical distribution of delta sleep inducing peptide in the rabbit brain and hypophysis.

Charnay Y, Bouras C, Vallet PG, Golaz J, Guntern R, Constantinidis J

Neuroendocrinology1 Feb 1989Cited by 18 (Europe PMC)

PMID2657475 (opens in a new tab)DOI10.1159/000125110 (opens in a new tab)PepBankPUB-02657475
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

No result from this study comes from a test of the peptide.

Natural levels measured8

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueOther

    In the rabbit, DSIP-like immunoreactivity was predominantly detected in the basal forebrain, hypothalamus and hypophysis.

    In plain wordsIn rabbits, the body's own DSIP-like material was found mainly in the basal forebrain, hypothalamus and pituitary.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableOverall distribution of DSIP-like immunoreactivity
    Study

    rabbitn: not reported in source

    Rabbit brain and hypophysis (immunohistochemistry)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    DSIP-like immunoreactivity was predominantly detected in the basal forebrain, hypothalamus and hypophysis.
    1 context sentence
    Summary · context
    The distribution of delta sleep inducing peptide (DSIP) in the rabbit brain has been studied with immunohistochemical techniques.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueOther

    In the rabbit, immunolabeled cell bodies were relatively few, even in colchicine-pretreated animals, and were mostly scattered through the ventrolateral septum, diagonal band of Broca and preoptic areas.

    In plain wordsIn rabbits, few cells held natural DSIP-like material, mostly in the septum, diagonal band and preoptic areas.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-immunoreactive cell bodies
    Study

    rabbitn: not reported in source

    Rabbit brain and hypophysis (immunohistochemistry)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Even in colchicine-pretreated animals, immunolabeled cell bodies were relatively few. They were mostly scattered through the ventrolateral septum, the diagonal band of Broca and preoptic areas.
    1 context sentence
    Summary · context
    The distribution of delta sleep inducing peptide (DSIP) in the rabbit brain has been studied with immunohistochemical techniques.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelEx vivo tissueOther

    In the rabbit, clusters of DSIP-positive cell bodies were found in the arcuate nucleus and adjacent lateral hypothalamic areas.

    In plain wordsIn rabbits, clusters of cells with natural DSIP-like material were found in the arcuate nucleus and nearby hypothalamus.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableClusters of DSIP-positive cell bodies
    Study

    rabbitn: not reported in source

    Rabbit brain and hypophysis (immunohistochemistry)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Clusters of positive cell bodies were also found in the arcuate nucleus and adjacent lateral hypothalamic areas.
    1 context sentence
    Summary · context
    The distribution of delta sleep inducing peptide (DSIP) in the rabbit brain has been studied with immunohistochemical techniques.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  4. 04LabEndogenous levelEx vivo tissueOther

    In the rabbit, large populations of varicose fibers and terminal-like structures were observed in the ventrolateral septum, preoptic areas, lamina terminalis and ventromedial hypothalamic nucleus.

    In plain wordsIn rabbits, many fibres with natural DSIP-like material were seen in the septum, preoptic areas and hypothalamus.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-immunoreactive varicose fibers
    Study

    rabbitn: not reported in source

    Rabbit brain and hypophysis (immunohistochemistry)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Large populations of varicose fibers and terminal-like structures were observed in the juxtaventricular zone of the ventrolateral septum, in the preoptic areas and lamina terminalis especially around the preoptic recess of the third ventricle and more caudally, in the ventromedial nucleus of the hypothalamus.
    1 context sentence
    Summary · context
    The distribution of delta sleep inducing peptide (DSIP) in the rabbit brain has been studied with immunohistochemical techniques.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  5. 05LabEndogenous levelEx vivo tissueOther

    In the rabbit, dense networks of immunolabeled fibers were visualized in the median eminence and pituitary stalk, close to capillaries.

    In plain wordsIn rabbits, dense fibres with natural DSIP-like material were found in the median eminence and pituitary stalk.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-immunoreactive fibers in median eminence and pituitary stalk
    Study

    rabbitn: not reported in source

    Rabbit brain and hypophysis (immunohistochemistry)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Dense networks of immunolabeled fibers were visualized in the median eminence and pituitary stalk where many fibers could be seen in close apposition to the capillaries.
    1 context sentence
    Summary · context
    The distribution of delta sleep inducing peptide (DSIP) in the rabbit brain has been studied with immunohistochemical techniques.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  6. 06LabEndogenous levelEx vivo tissueOther

    In the rabbit, many DSIP-immunoreactive fibers were observed in the subfornical organ.

    In plain wordsIn rabbits, many fibres with natural DSIP-like material were seen in the subfornical organ.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-immunoreactive fibers in subfornical organ
    Study

    rabbitn: not reported in source

    Rabbit brain and hypophysis (immunohistochemistry)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Many DSIP-immunoreactive fibers were observed in the subfornical organ.
    1 context sentence
    Summary · context
    The distribution of delta sleep inducing peptide (DSIP) in the rabbit brain has been studied with immunohistochemical techniques.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  7. 07LabEndogenous levelEx vivo tissueOther

    In the rabbit, other extra-hypothalamic regions such as the hippocampus and medial habenula showed a low-to-moderate density of immunoreactive fibers.

    In plain wordsIn rabbits, some other brain areas had a small to moderate amount of fibres with natural DSIP-like material.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-immunoreactive fibers in other extra-hypothalamic regions
    Study

    rabbitn: not reported in source

    Rabbit brain and hypophysis (immunohistochemistry)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Other extra-hypothalamic regions displaying a low-to-moderate density of immunoreactive fibers were the indusium griseum, the hippocampus, the fimbria of the fornix, the subcommissural organ, the medial habenula and, occasionally, the medial periaqueductal gray.
    1 context sentence
    Summary · context
    The distribution of delta sleep inducing peptide (DSIP) in the rabbit brain has been studied with immunohistochemical techniques.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  8. 08LabEndogenous levelEx vivo tissueOther

    In the rabbit, most cells of the pars intermedia and a few cells of the pars distalis of the anterior pituitary were DSIP-immunoreactive.

    In plain wordsIn rabbits, most cells in the pituitary intermediate part and a few in the front part held natural DSIP-like material.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-immunoreactive pituitary cells
    Study

    rabbitn: not reported in source

    Rabbit brain and hypophysis (immunohistochemistry)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Most cells of the pars intermedia and a few cells of the pars distalis of the anterior pituitary were DSIP-immunoreactive.
    1 context sentence
    Summary · context
    The distribution of delta sleep inducing peptide (DSIP) in the rabbit brain has been studied with immunohistochemical techniques.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

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