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Study · Non-randomized trial · 1989

2 results

Vasotocin improves intelligence and attention in mentally retarded children.

Goldstein R, Joja O, Psatta DM, Petrescu M, Paraschiv I, Popa M

Physiology & behavior1 Dec 1989Cited by 3 (Europe PMC)

PMID2634261 (opens in a new tab)DOI10.1016/0031-9384(89)90199-6 (opens in a new tab)PepBankPUB-02634261
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In mentally retarded prepubertal children, oxytocin did not significantly increase the intelligence quotient after six months, unlike arginine vasotocin.

    In plain wordsIn children with intellectual disability, oxytocin did not raise IQ scores, while vasotocin did.

    Peptide
    Oxytocin
    Outcome
    No significant changeIntelligence quotient
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · six monthsAs given in this study (human).

    Source sentences

    Summary
    In mentally retarded (MR) prepubertal children, investigated both before and after six months of treatment, synthetic arginine vasotocin (AVT) (10(-6) mg/day/0.1 ml, intranasally), but not oxytocin or saline alone, significantly increased the intelligence quotient (IQ) and improved the attention par…
  2. 02HumanNon-randomized trialEfficacy outcome

    In mentally retarded prepubertal children, oxytocin did not significantly improve attention parameters after six months, unlike arginine vasotocin.

    In plain wordsIn children with intellectual disability, oxytocin did not improve attention, while vasotocin did.

    Peptide
    Oxytocin
    Outcome
    No significant changeAttention parameters
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · six monthsAs given in this study (human).

    Source sentences

    Summary
    In mentally retarded (MR) prepubertal children, investigated both before and after six months of treatment, synthetic arginine vasotocin (AVT) (10(-6) mg/day/0.1 ml, intranasally), but not oxytocin or saline alone, significantly increased the intelligence quotient (IQ) and improved the attention par…

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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