In explanted hamster follicles, enclomiphene did not significantly reduce the proportion of immature oocytes over the tested concentrations.
In plain wordsIn lab tests with hamster follicles, enclomiphene did not significantly reduce the proportion of immature oocytes.
- Peptide
- Enclomiphene
- Outcome
- No significant changeProportion of immature oocytes
- Study
hamstern: not reported in source
Explanted antral follicles- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
- Studied dose
- 0-500 microM · intrafollicular injection · 6 or 10 hAs given in this study (hamster).
Source sentences
The % GV was not significantly reduced by intrafollicular injection of either of the anti-oestrogens over the concentration ranges tested, or of the oestradiol-specific antiserum, which was injected in an amount adequate to bind all oestradiol accumulated during the incubation.
2 context sentences(design, population, supporting numbers)
the anti-oestrogens, tamoxifen (0-200 microM) or enclomiphene citrate (0-500 microM)
Mature antral follicles were collected from PMSG-primed hamsters before the LH surge on Day 4 of the oestrous cycle and were incubated individually for 6 or 10 h under 95% O2 and 5% CO2.