Effect of intracerebrally injected aminophylline, vinpocetinum, vasoactive intestinal peptide and onion extract on breathing pattern of rats.

Vertes C, Debreczeni LA

Zeitschrift fur Erkrankungen der Atmungsorgane1 Jan 1989

PMID2588686PepBankPUB-02588686

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

01AnimalAnimal study (in vivo)Efficacy outcome
In rats, intracerebral VIP increased tidal volume.
In plain wordsIn rats, VIP injected into the brain increased the volume of each breath.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
IncreaseTidal volume
Study
ratn: not reported in source
Outcome group
Respiratory function · Respiratory
Studied dose
5 micrograms · intracerebralAs given in this study (rat).
Source sentences
Summary
VIP increased the tidal volume, minute ventilation and the respiratory drive.
1 context sentence(design, population, supporting numbers)
Summary · context
The purpose of this study was to investigate the effect of intracerebrally injected aminophylline (3 microM), Vinpocetinum (0.1 mg/kg), VIP (5 micrograms) and onion oils (30 microliters of extracts) on the respiratory center and on the resistance of lower airways of rats.
Report a problemFND-0258868601
02AnimalAnimal study (in vivo)Efficacy outcome
In rats, intracerebral VIP increased minute ventilation.
In plain wordsIn rats, VIP injected into the brain increased the amount of air breathed per minute.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
IncreaseMinute ventilation
Study
ratn: not reported in source
Outcome group
Respiratory function · Respiratory
Studied dose
5 micrograms · intracerebralAs given in this study (rat).
Source sentences
Summary
VIP increased the tidal volume, minute ventilation and the respiratory drive.
1 context sentence(design, population, supporting numbers)
Summary · context
The purpose of this study was to investigate the effect of intracerebrally injected aminophylline (3 microM), Vinpocetinum (0.1 mg/kg), VIP (5 micrograms) and onion oils (30 microliters of extracts) on the respiratory center and on the resistance of lower airways of rats.
Report a problemFND-0258868602
03AnimalAnimal study (in vivo)Efficacy outcome
In rats, intracerebral VIP increased the respiratory drive.
In plain wordsIn rats, VIP injected into the brain increased the drive to breathe.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
IncreaseRespiratory drive
Study
ratn: not reported in source
Outcome group
Respiratory function · Respiratory
Studied dose
5 micrograms · intracerebralAs given in this study (rat).
Source sentences
Summary
VIP increased the tidal volume, minute ventilation and the respiratory drive.
1 context sentence(design, population, supporting numbers)
Summary · context
The purpose of this study was to investigate the effect of intracerebrally injected aminophylline (3 microM), Vinpocetinum (0.1 mg/kg), VIP (5 micrograms) and onion oils (30 microliters of extracts) on the respiratory center and on the resistance of lower airways of rats.
Report a problemFND-0258868603

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
12 Oct 2026, 12:58 UTC
Study results updated
Version 1
9 Oct 2026, 12:41 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

MeSH terms

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