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Study · Animal study (in vivo) · guinea pig · 1989

2 results

Enclomiphene induces luteolysis in the nonpregnant guinea pig.

Westfahl PK

Experientia1 Jan 1989

PMID2492231 (opens in a new tab)DOI10.1007/bf01990463 (opens in a new tab)PepBankPUB-02492231
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In guinea pigs, enclomiphene caused premature luteolysis during the early or mid-luteal phase, with lower potency than estradiol.

    In plain wordsIn guinea pigs, enclomiphene caused premature luteolysis, with lower potency than estradiol.

    Peptide
    Enclomiphene
    Outcome
    DecreaseLuteolytic potency versus estradiol
    Study

    guinea pign: not reported in source

    Nonpregnant guinea pig
    Comparator
    Estradiol
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Enclomiphene caused premature luteolysis when administered during the early or mid-luteal phase of the cycle, but was not as potent as estradiol.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In guinea pigs, the uterus mediated enclomiphene-induced luteolysis.

    In plain wordsIn guinea pigs, the uterus mediated enclomiphene-induced luteolysis.

    Peptide
    Enclomiphene
    Outcome
    Not applicableUterine mediation of luteolysis
    Study

    guinea pign: not reported in source

    Nonpregnant guinea pig
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The luteolytic effect of enclomiphene was mediated by the uterus, as has been shown for estradiol.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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