A comparative study of the localization of vasoactive intestinal peptide- and substance P-like immunoreactivities in the submandibular salivary glands of mice.

Letić-Gavrilović A, Shibaike S, Fukai S, Naruse S, Abe K

Shika Kiso Igakkai zasshi = Japanese journal of oral biology1 Dec 1989

PMID2485109DOI10.2330/joralbiosci1965.31.705PepBankPUB-02485109

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01AnimalEndogenous levelAnimal study (in vivo)Other
In male Balb/c mice, VIP-like immunoreactivity was present in the submandibular salivary gland.
In plain wordsIn mice, the body's own VIP-like protein was found in the submandibular salivary gland.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
Not applicableVIP-like immunoreactivity in submandibular gland
Study
mousen: not reported in source
submandibular salivary gland, immunocytochemistry
Outcome group
Endogenous peptide levels · Gastrointestinal
Source sentences
Summary
Both VIP- and SP-like immunoreactivities were positive in the SMG of Balb/c male mice at 4 to 5 weeks of age.
1 context sentence(design, population, supporting numbers)
Summary · context
The localization of vasoactive intestinal peptide (VIP)- and substance P (SP)-like immunoreactivities within the submandibular salivary glands (SMG) of Balb/c male mice at 4 to 5 weeks of age were investigated.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0248510901
02AnimalEndogenous levelAnimal study (in vivo)Other
In male Balb/c mice, VIP-like immunoreactivity was found in dense plexuses around the salivary duct, small nerves around glandular acini and the nerve cell bodies of the submaxillary ganglion.
In plain wordsIn mice, the body's own VIP-like protein was found in nerves around the salivary ducts and glands, and in a nerve cell cluster.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
Not applicableLocalization of VIP-like immunoreactivity
Study
mousen: not reported in source
submandibular salivary gland, immunocytochemistry
Outcome group
Endogenous peptide levels · Gastrointestinal
Source sentences
Summary
The VIP-like immunoreactivity was found in the dense plexuses around the salivary duct and in the small scattered nerves surrounding glandular acini, and particularly in the nerve cell bodies of the submaxillary ganglion.
1 context sentence(design, population, supporting numbers)
Summary · context
The localization of vasoactive intestinal peptide (VIP)- and substance P (SP)-like immunoreactivities within the submandibular salivary glands (SMG) of Balb/c male mice at 4 to 5 weeks of age were investigated.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0248510902

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
12 Oct 2026, 12:58 UTC
Study results updated
Version 1
9 Oct 2026, 12:41 UTC
First added · source update from Europe PMC

Subjects

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