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Study · In vitro (cells) · rat · 1988

1 result

Thymosin fraction 5 (TF5) stimulates secretion of adrenocorticotropic hormone (ACTH) from cultured rat pituitaries.

McGillis JP, Hall NR, Goldstein AL

Life sciences1 Jan 1988Cited by 14 (Europe PMC)

PMID2453772 (opens in a new tab)DOI10.1016/0024-3205(88)90378-5 (opens in a new tab)PepBankPUB-02453772
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In cultured rat pituitary cells, FTS had no effect on ACTH secretion.

    In plain wordsIn lab tests with rat pituitary cells, FTS did not change ACTH release.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeACTH secretion
    Study

    ratn: not reported in source

    Cultured pituitary monolayers
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    None of these factors had any effect on pituitary ACTH secretion.
    2 context sentences
    Summary · context
    These included thymosin (TSN) alpha 1, alpha 11, and beta 4, prothymosin alpha (PT alpha, thymopoeitin 5 (TP5), factuer thymique serique (FTS), interferon alpha (INF alpha), INF gamma, interleukin 1 (IL-1), and interleukin 2 (IL-2).
    Summary · context
    Cultured rat pituitary monolayers were used to determine if the effect is mediated by stimulation of ACTH secretion from the pituitary.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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