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Study · Measured the body's own peptide · 1987

8 results

Vasoactive intestinal polypeptide cerebrospinal fluid-contacting neurons of the monkey and cat spinal central canal.

LaMotte CC

The Journal of comparative neurology1 Apr 1987Cited by 29 (Europe PMC)

PMID2438312 (opens in a new tab)DOI10.1002/cne.902580405 (opens in a new tab)PepBankPUB-02438312
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

No result from this study comes from a test of the peptide.

Natural levels measured8

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In the cat and monkey spinal cord, neurons next to the central canal were immunoreactive for VIP.

    In plain wordsIn cats and monkeys, nerve cells next to the spinal canal contained the body's own VIP.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableVIP-immunoreactive neurons next to the central canal
    Study

    cat and monkeyn: not reported in source

    Spinal cord central canal
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Neurons immediately adjacent to the central canal were demonstrated in the cat and monkey to be immunoreactive for the peptide vasoactive intestinal polypeptide (VIP), by means of the peroxidase antiperoxidase method.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In the cat and monkey spinal cord, most VIP-immunoreactive cells were in the thoracic and sacral segments, with a few at each level.

    In plain wordsIn cats and monkeys, most spinal cells with the body's own VIP were in the thoracic and sacral parts of the cord.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableSegmental location of VIP neurons
    Study

    cat and monkeyn: not reported in source

    Spinal cord central canal
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Most of the cells were found in the thoracic and sacral segments, although a few were present at each level.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In the cat and monkey spinal cord, electron microscopy showed VIP axons and varicosities containing small round clear vesicles and dense core vesicles.

    In plain wordsIn cats and monkeys, electron microscopy showed nerve endings with the body's own VIP that held small sacs of two types.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableVIP axons and vesicles by electron microscopy
    Study

    cat and monkeyn: not reported in source

    Spinal cord central canal
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Electron microscopy demonstrated VIP axons and varicosities containing small round clear vesicles and dense core vesicles.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In the cat and monkey spinal cord, VIP processes were in desmosomal contact with ependymal cells and in direct contact with the CSF space.

    In plain wordsIn cats and monkeys, nerve fibres with the body's own VIP touched the fluid space of the spinal canal.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableContact of VIP processes with ependymal cells and CSF
    Study

    cat and monkeyn: not reported in source

    Spinal cord central canal
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    These processes were in desmosomal contact with ependymal cells and in direct contact with the CSF space.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  5. 05AnimalEndogenous levelAnimal study (in vivo)Other

    In the cat and monkey spinal cord, VIP processes were also found along the pial surface at each level.

    In plain wordsIn cats and monkeys, nerve fibres with the body's own VIP were also found on the outer surface of the spinal cord.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableVIP processes along the pial surface
    Study

    cat and monkeyn: not reported in source

    Spinal cord pial surface
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    VIP processes were also found along the pial surface of the spinal cord at each level.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  6. 06AnimalEndogenous levelAnimal study (in vivo)Other

    In the cat sacral spinal cord, a prominent network of intensely labelled VIP processes extended in parallel along the canal surface.

    In plain wordsIn cats, a dense network of nerve fibres with the body's own VIP ran along the sacral spinal canal.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableSacral cord network of VIP processes in the cat
    Study

    catn: not reported in source

    Sacral spinal cord
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Most prominent in the sacral cord of the cat was a massive intricate network of intensely labelled processes extending in parallel along the canal surface.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  7. 07AnimalEndogenous levelAnimal study (in vivo)Other

    In the cat and monkey thoracic spinal cord, VIP neurons next to the central canal were multipolar and either ependymal or subependymal.

    In plain wordsIn cats and monkeys, nerve cells with the body's own VIP next to the thoracic spinal canal had several branches.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableMorphology of thoracic VIP neurons at the central canal
    Study

    cat and monkeyn: not reported in source

    Spinal cord central canal
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    The thoracic neurons were multipolar and either ependymal or subependymal

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  8. 08AnimalEndogenous levelAnimal study (in vivo)Other

    In the sacral cord of the cat and monkey, VIP neurons along the central canal were of several types: round or multipolar, and subependymal, within the ependyma, or supraependymal.

    In plain wordsIn cats and monkeys, nerve cells with the body's own VIP along the sacral spinal canal were of several types.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableTypes of sacral VIP neurons at the central canal
    Study

    cat and monkeyn: not reported in source

    Spinal cord central canal
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    In the sacral cord, the VIP neurons that lie along the central canal were of several types. They were round or multipolar and were either subependymal, within the ependyma, or supraependymal.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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