A radioimmunoassay for thymosin alpha 1 that detects the native polypeptide, prothymosin alpha.

Haritos AA, Horecker BL

Journal of immunological methods1 Aug 1985Cited by 27 (Europe PMC)

PMID2410515DOI10.1016/0022-1759(85)90204-2PepBankPUB-02410515

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

01LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other
A radioimmunoassay developed for thymosin alpha‑1 also quantified the intact native polypeptide prothymosin alpha.
In plain wordsIn lab tests, an assay built for thymosin alpha‑1 can also measure the larger natural polypeptide prothymosin alpha.
Peptide
Thymosin alpha-1
Outcome
Not applicableRadioimmunoassay detection of prothymosin alpha
Study
n: not reported in source
radioimmunoassay
Outcome group
Receptor activity and mechanism · Pharmacology
Source sentences
Summary
A radioimmunoassay, developed for thymosin alpha 1, can also be utilized for the quantitation of the intact native polypeptide, prothymosin alpha
In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.
Report a problemFND-0241051501
02LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other
The major epitope of the radioimmunoassay includes residues 1-10 at the NH2-terminus of thymosin alpha‑1.
In plain wordsIn lab tests, the assay recognises the first ten residues at the start of thymosin alpha‑1.
Peptide
Thymosin alpha-1
Outcome
Not applicableAssay epitope
Study
n: not reported in source
radioimmunoassay
Outcome group
Receptor activity and mechanism · Pharmacology
Source sentences
Summary
The major epitope was characterized and found to include residues 1-10 at the NH2-terminus of thymosin alpha 1.
In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.
Report a problemFND-0241051502
03LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other
The radioimmunoassay detected as little as 5 pmol of prothymosin alpha in tissue extracts.
In plain wordsIn lab tests, the assay detected as little as 5 pmol of prothymosin alpha in tissue extracts.
Peptide
Thymosin alpha-1
Outcome
Not applicableAssay detection limit for prothymosin alpha in tissue extracts
Study
n: not reported in source
radioimmunoassay
Outcome group
Receptor activity and mechanism · Pharmacology
Measurements
detection limit
5 pmol
prothymosin alpha in tissue extracts
Source sentences
Summary
As little as 5 pmol of prothymosin alpha can be detected in tissue extracts with this radioimmunoassay.
In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.
Report a problemFND-0241051503

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 3Current
10 Oct 2026, 08:55 UTC
Study results updated
Version 2
9 Oct 2026, 03:03 UTC
Study data updated · source update from Europe PMC
Version 1
9 Oct 2026, 03:02 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

Journal Article

MeSH terms

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