In isolated rabbit hearts, DSIP enhanced the negative chronotropic effect of acetylcholine.
In plain wordsIn isolated rabbit hearts, DSIP made the slowing effect of acetylcholine on heart rate stronger.
- Outcome
- IncreaseNegative chronotropic effect of acetylcholine
- Study
rabbitn = 51
isolated heart- Outcome group
- Heart function · Cardiovascular
- Studied dose
- 6 X 10(-6) M/lAs given in this study (rabbit).
Source sentences
This peptide enhances negative chronotropic effect of acetylcholine
1 context sentence(design, population, supporting numbers)
Experiments on 51 isolated rabbit hearts have documented, that delta sleep-inducing peptide (6 X 10(-6) M/l) has a modulating effect on the mediators influencing the heart.