Neurohypophysial hormones and cardiac activity in the frog, Rana tigrina, and in the snake, Ptyas mucosa.

Chiu KW, Lee YC, Pang PK

General and comparative endocrinology1 Apr 1990Cited by 5 (Europe PMC)

PMID2332147DOI10.1016/0016-6480(90)90055-qPepBankPUB-02332147

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

01LabEx vivo tissueActivity measurement
In isolated frog atria, oxytocin produced dose-related positive chronotropic responses.
In plain wordsIn lab tests on frog heart tissue, oxytocin raised the beat rate, and the rise grew with the dose.
Peptide
Oxytocin
Outcome
IncreaseChronotropic response in frog atria
Study
frog (Rana tigrina)n: not reported in source
isolated atrial preparations
Outcome group
Heart function · Cardiovascular
Studied dose
Dose not stated
Source sentences
Summary
Arginine vasopressin (AVP), vasotocin (AVT), isotocin (ISN), mesotocin (MSN), and oxytocin (OXY) produced dose-related positive chronotropic and inotropic responses in the frog atria.
1 context sentence(design, population, supporting numbers)
Summary · context
The cardiac effects of neurohypophysial hormones (NH) in the frog, Rana tigrina, and in the snake, Ptyas mucosa, were studied in isolated atrial preparations.
Report a problemFND-0233214701
02LabEx vivo tissueActivity measurement
In isolated frog atria, oxytocin produced dose-related positive inotropic responses.
In plain wordsIn lab tests on frog heart tissue, oxytocin raised the beat force, and the rise grew with the dose.
Peptide
Oxytocin
Outcome
IncreaseInotropic response in frog atria
Study
frog (Rana tigrina)n: not reported in source
isolated atrial preparations
Outcome group
Heart function · Cardiovascular
Studied dose
Dose not stated
Source sentences
Summary
Arginine vasopressin (AVP), vasotocin (AVT), isotocin (ISN), mesotocin (MSN), and oxytocin (OXY) produced dose-related positive chronotropic and inotropic responses in the frog atria.
1 context sentence(design, population, supporting numbers)
Summary · context
The cardiac effects of neurohypophysial hormones (NH) in the frog, Rana tigrina, and in the snake, Ptyas mucosa, were studied in isolated atrial preparations.
Report a problemFND-0233214702
03LabEx vivo tissueActivity measurement
In isolated snake atria, oxytocin produced dose-related positive inotropic changes.
In plain wordsIn lab tests on snake heart tissue, oxytocin raised the beat force, and the rise grew with the dose.
Peptide
Oxytocin
Outcome
IncreaseInotropic response in snake atria
Study
snake (Ptyas mucosa)n: not reported in source
isolated atrial preparations
Outcome group
Heart function · Cardiovascular
Studied dose
Dose not stated
Source sentences
Summary
In the snake, AVP, AVT, MSN, and OXY produced dose-related positive inotropic but not chronotropic changes.
1 context sentence(design, population, supporting numbers)
Summary · context
The cardiac effects of neurohypophysial hormones (NH) in the frog, Rana tigrina, and in the snake, Ptyas mucosa, were studied in isolated atrial preparations.
Report a problemFND-0233214703
04LabEx vivo tissueActivity measurement
In isolated snake atria, oxytocin did not produce chronotropic changes.
In plain wordsIn lab tests on snake heart tissue, oxytocin did not change the beat rate.
Peptide
Oxytocin
Outcome
No significant changeChronotropic response in snake atria
Study
snake (Ptyas mucosa)n: not reported in source
isolated atrial preparations
Outcome group
Heart function · Cardiovascular
Studied dose
Dose not stated
Source sentences
Summary
In the snake, AVP, AVT, MSN, and OXY produced dose-related positive inotropic but not chronotropic changes.
1 context sentence(design, population, supporting numbers)
Summary · context
The cardiac effects of neurohypophysial hormones (NH) in the frog, Rana tigrina, and in the snake, Ptyas mucosa, were studied in isolated atrial preparations.
Report a problemFND-0233214704
05LabEx vivo tissueActivity measurement
In isolated snake atria, oxytocin was the most potent of the neurohypophysial hormones tested.
In plain wordsIn lab tests on snake heart tissue, oxytocin was the strongest of the related hormones tested.
Peptide
Oxytocin
Outcome
Not applicablePotency of oxytocin in snake atria
Study
snake (Ptyas mucosa)n: not reported in source
isolated atrial preparations
Outcome group
Heart function · Cardiovascular
Studied dose
Dose not stated
Source sentences
Summary
OXY was the most potent.
1 context sentence(design, population, supporting numbers)
Summary · context
The cardiac effects of neurohypophysial hormones (NH) in the frog, Rana tigrina, and in the snake, Ptyas mucosa, were studied in isolated atrial preparations.
Report a problemFND-0233214705

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 20:03 UTC
Study results updated
Version 1
9 Oct 2026, 02:53 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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MeSH terms

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