Skip to content

Study · Measured the body's own peptide · 1990

5 results

Relaxin and prostaglandin on oxytocin secretion from bovine luteal cells during different stages of gestation.

Musah AH, Schwabe C, Anderson LL

Acta endocrinologica1 Mar 1990Cited by 1 (Europe PMC)

PMID2327218 (opens in a new tab)DOI10.1530/acta.0.1220396 (opens in a new tab)PepBankPUB-02327218
Publisher pagePubMedAsk about this study
Jump to 5 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Other

    In cultured bovine luteal cells, basal oxytocin secretion was similar for all stages of gestation.

    In plain wordsIn cow ovary cells, the body's own oxytocin release without treatment was similar at all stages of pregnancy.

    Peptide
    Oxytocin
    Outcome
    No significant changeBasal oxytocin secretion across stages of gestation
    Study

    cattlen: not reported in source

    cultured bovine luteal cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Measurements

    basal oxytocin secretion
    22 to 31 pmol/l
    all stages of gestation

    Source sentences

    Summary
    Basal oxytocin secretion was similar (22-31 pmol/l, p less than 0.05) for all stages of gestation (days 100, 145, 160, 185, 200, 210, and 240).
    2 context sentences
    Summary · context
    Bovine luteal cells (10(5)) were cultured for 24 h without treatment and with medium-hormone replacement every 24 h.
    Summary · context
    Oxytocin was quantified by radioimmunoassay of the culture media.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelIn vitro (cells)Other

    In cultured bovine luteal cells, porcine relaxin induced a dose-dependent suppression of oxytocin release.

    In plain wordsIn cow ovary cells, relaxin lowered the release of the body's own oxytocin as the dose went up.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin release with increasing relaxin
    Study

    cattlen: not reported in source

    cultured bovine luteal cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Measurements

    oxytocin release
    138 pmol/l
    no relaxin, cells from 240-day-old corpora lutea
    oxytocin release
    15 pmol/l
    167 nmol/l relaxin, cells from 240-day-old corpora lutea

    Source sentences

    Summary
    Relaxin induced a dose-dependent suppression of oxytocin release.
    3 context sentences
    Summary · context
    After 24 h of incubation, addition of 0, 16.7, 83.5, and 167 nmol/l porcine relaxin (3000 U/mg) induced 54 +/- 4, 105 +/- 16, 47 +/- 4, and 38 +/- 4 pmol/l of oxytocin in cells from 160-day-old corpora lutea and 138 +/- 12, 21 +/- 2, 19 +/- 3, and 15 +/- 2 pmol/l oxytocin in cells from 240-day-old corpora lutea.
    Summary · context
    Bovine luteal cells (10(5)) were cultured for 24 h without treatment and with medium-hormone replacement every 24 h.
    Summary · context
    Oxytocin was quantified by radioimmunoassay of the culture media.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelIn vitro (cells)Other

    In cultured bovine luteal cells, cloprostenol induced a marked increase in oxytocin release.

    In plain wordsIn cow ovary cells, cloprostenol clearly raised the release of the body's own oxytocin.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin release with cloprostenol
    Study

    cattlen: not reported in source

    cultured bovine luteal cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Measurements

    oxytocin release
    208 pmol/l
    160-day-old corpora lutea, 2 micromol/l cloprostenol
    oxytocin release
    371 pmol/l
    240-day-old corpora lutea, 2 micromol/l cloprostenol

    Source sentences

    Summary
    From luteal cells of 160- and 240-day-old corpora lutea, 2 micromol/l cloprostenol induced a marked increase (p less than 0.01) of 208 +/- 39 and 371 +/- 34 pmol/l oxytocin, respectively.
    2 context sentences
    Summary · context
    Bovine luteal cells (10(5)) were cultured for 24 h without treatment and with medium-hormone replacement every 24 h.
    Summary · context
    Oxytocin was quantified by radioimmunoassay of the culture media.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  4. 04LabEndogenous levelIn vitro (cells)Other

    In cultured bovine luteal cells, 167 nmol/l relaxin did not prevent cloprostenol-induced oxytocin secretion during the first 48 h.

    In plain wordsIn cow ovary cells, relaxin did not stop the cloprostenol-driven release of the body's own oxytocin in the first two days.

    Peptide
    Oxytocin
    Outcome
    No significant changeCloprostenol-induced oxytocin release with relaxin during first 48 h
    Study

    cattlen: not reported in source

    cultured bovine luteal cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Addition of 167 nmol/l relaxin did not prevent cloprostenol-induced oxytocin secretion during the first 48 h
    2 context sentences
    Summary · context
    Bovine luteal cells (10(5)) were cultured for 24 h without treatment and with medium-hormone replacement every 24 h.
    Summary · context
    Oxytocin was quantified by radioimmunoassay of the culture media.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  5. 05LabEndogenous levelIn vitro (cells)Other

    In cultured bovine luteal cells, oxytocin decreased in day 3 cultures given relaxin with cloprostenol.

    In plain wordsIn cow ovary cells, the body's own oxytocin release fell on day 3 when relaxin was added with cloprostenol.

    Peptide
    Oxytocin
    Outcome
    DecreaseCloprostenol-induced oxytocin release with relaxin on day 3
    Study

    cattlen: not reported in source

    cultured bovine luteal cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    but a decrease (p less than 0.05) in oxytocin occurred in day 3 cell cultures.
    2 context sentences
    Summary · context
    Bovine luteal cells (10(5)) were cultured for 24 h without treatment and with medium-hormone replacement every 24 h.
    Summary · context
    Oxytocin was quantified by radioimmunoassay of the culture media.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.