Skip to content

Study · Animal study (in vivo) · rat · 1990

7 results

[The effect of the delta-sleep peptide on the adrenaline level in rat tissues under normal conditions and during cold stress].

Bondarenko TI, Krichevskaia AA, Sheĭkina IV, Kiriukhina EV

Ukrainskii biokhimicheskii zhurnal (1978)1 Sept 1990Cited by 1 (Europe PMC)

PMID2270622 (opens in a new tab)PepBankPUB-02270622
Publisher pageAsk about this study
Jump to 7 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

7 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In intact rats, a single DSIP dose of 12 microgram/100 g raised brain adrenalin content at 1, 3, 6 and 24 h, with no change two and three days later.

    In plain wordsIn rats, one DSIP dose raised brain adrenalin for the first day, with no change after two and three days.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseBrain adrenalin content in intact rats over time
    Study

    ratn: not reported in source

    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    12 microgram/100 gAs given in this study (rat).

    Source sentences

    Summary
    A single administration of the delta-sleep inducing peptide (DSIP) in a dose of 12 microgram/100 g to intact animals makes the adrenalin content in the brain higher 1, 3, 6 and 24h after administration; two and three days later the adrenalin content in the brain does not change.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In intact rats, DSIP increased liver adrenalin content at 1, 3, 6 h and 1, 2, 3 days after administration.

    In plain wordsIn rats, DSIP raised adrenalin in the liver for up to three days.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseLiver adrenalin content in intact rats over time
    Study

    ratn: not reported in source

    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    12 microgram/100 gAs given in this study (rat).

    Source sentences

    Summary
    The amount of adrenalin in the liver of the same animals increases 1, 3, 6 h and 1, 2, 3 days after DSIP administration.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats, intraperitoneal DSIP increased adrenalin level in the adrenal glands an hour and a day after administration.

    In plain wordsIn rats, DSIP given by injection into the abdomen raised adrenalin in the adrenal glands an hour and a day later.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseAdrenal gland adrenalin content in intact rats at 1 h and 1 day
    Study

    ratn: not reported in source

    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Intraperitoneal administration of DSIP induces an increase of the adrenalin level in the adrenal glands of rats an hour and a day after administration.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In rats, adrenaline in the adrenal glands decreased by 41% two days after DSIP, and was unchanged at 3, 6 h and 3 days.

    In plain wordsIn rats, adrenaline in the adrenal glands fell two days after DSIP, and did not change at some other times.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseAdrenal gland adrenaline at two days after DSIP
    Study

    ratn: not reported in source

    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    Dose not stated

    Measurements

    adrenaline decrease
    41%
    adrenal glands, 2 days after DSIP

    Source sentences

    Summary
    Two days later the level of adrenaline decreases by 41%; 3, 6 h and 3 days after DSIP administration the content of adrenaline remains unchanged.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In rats under cold stress, DSIP (12 micrograms/100 g) increased the brain adrenalin content by 129 compared with control; the abstract gives no unit for this value.

    In plain wordsIn rats under cold stress, DSIP raised brain adrenalin compared with control.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseBrain adrenalin content in cold-stressed rats
    Study

    ratn: not reported in source

    Comparator
    Control
    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    12 micrograms/100 gAs given in this study (rat).

    Source sentences

    Summary
    As a result of the DSIP administration in a dose of 12 micrograms/100 g to the animals in the state of cold stress, the content of adrenalin increases in the rat brain
  6. 06AnimalAnimal study (in vivo)Efficacy outcome

    In rats under cold stress, DSIP (12 micrograms/100 g) increased the liver adrenalin content by 300 compared with control; the abstract gives no unit for this value.

    In plain wordsIn rats under cold stress, DSIP raised liver adrenalin compared with control.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseLiver adrenalin content in cold-stressed rats
    Study

    ratn: not reported in source

    Comparator
    Control
    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    12 micrograms/100 gAs given in this study (rat).

    Source sentences

    Summary
    As a result of the DSIP administration in a dose of 12 micrograms/100 g to the animals in the state of cold stress, the content of adrenalin increases in the rat brain by 129, in the liver--by 300, adrenal glands--by 44% as compared with the control.
  7. 07AnimalAnimal study (in vivo)Efficacy outcome

    In rats under cold stress, DSIP (12 micrograms/100 g) increased the adrenal gland adrenalin content by 44% compared with control.

    In plain wordsIn rats under cold stress, DSIP raised adrenalin in the adrenal glands compared with control.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseAdrenal gland adrenalin content in cold-stressed rats
    Study

    ratn: not reported in source

    Comparator
    Control
    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    12 micrograms/100 gAs given in this study (rat).

    Measurements

    adrenalin increase
    44%
    adrenal glands, cold stress

    Source sentences

    Summary
    As a result of the DSIP administration in a dose of 12 micrograms/100 g to the animals in the state of cold stress, the content of adrenalin increases in the rat brain by 129, in the liver--by 300, adrenal glands--by 44% as compared with the control.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.