Immunocytochemical localization of oxytocin in corpora lutea and luteinized cysts from anoestrous ewes stimulated with gonadotrophin-releasing hormone.

Gilbert CL, Hunter MG, Southee JA, Wathes DC

Cell and tissue research1 Oct 1990Cited by 2 (Europe PMC)

PMID2257607DOI10.1007/bf00327757PepBankPUB-02257607

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01AnimalEndogenous levelAnimal study (in vivo)Other
In ewes given gonadotrophin-releasing hormone, all corpora lutea and luteinized cysts stained for oxytocin immunoreactivity, with variable intensity.
In plain wordsIn ewes given GnRH, all corpora lutea and cysts in the ovary showed the body's own oxytocin, with varying strength.
Peptide
Oxytocin
Outcome
Not applicableOxytocin immunoreactivity in corpora lutea and luteinized cysts
Study
sheep (Romney Marsh ewes)n: not reported in source
in vivo, ovarian tissue
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
All corpora lutea and luteinized cysts showed staining for oxytocin-immunoreactivity although the staining intensity was variable.
2 context sentences(design, population, supporting numbers)
Summary · context
Anoestrous Romney Marsh ewes with or without progesterone pretreatment were injected with multiple low-doses of gonadotrophin-releasing hormone followed by a single, larger bolus.
Summary · context
Ewes were slaughtered on day 3 or 5 after the bolus injection, and the ovaries were collected for histology and immunocytochemical examination for oxytocin-immunoreactivity.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0225760701
02AnimalEndogenous levelAnimal study (in vivo)Other
In corpora lutea from ewes with a normal progesterone profile, oxytocin was restricted to large luteal cells.
In plain wordsIn ewes with a normal progesterone pattern, the body's own oxytocin was found only in large cells of the corpus luteum.
Peptide
Oxytocin
Outcome
Not applicableOxytocin immunoreactivity in corpora lutea of normal ewes
Study
sheep (Romney Marsh ewes)n: not reported in source
in vivo, ovarian tissue
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
In corpora lutea from 'normal' ewes oxytocin was restricted to large luteal cells.
2 context sentences(design, population, supporting numbers)
Summary · context
Anoestrous Romney Marsh ewes with or without progesterone pretreatment were injected with multiple low-doses of gonadotrophin-releasing hormone followed by a single, larger bolus.
Summary · context
Ewes were slaughtered on day 3 or 5 after the bolus injection, and the ovaries were collected for histology and immunocytochemical examination for oxytocin-immunoreactivity.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0225760702
03AnimalEndogenous levelAnimal study (in vivo)Other
In tissue from ewes with an abnormal progesterone profile, many atypical elongated cells stained for oxytocin immunoreactivity.
In plain wordsIn ewes with an abnormal progesterone pattern, many oddly shaped ovary cells also showed the body's own oxytocin.
Peptide
Oxytocin
Outcome
Not applicableOxytocin immunoreactivity in atypical cells of abnormal ewes
Study
sheep (Romney Marsh ewes)n: not reported in source
in vivo, ovarian tissue
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
In addition tissues from 'abnormal' ewes also contained many cells with an atypical elongated shape which stained for oxytocin-immunoreactivity.
2 context sentences(design, population, supporting numbers)
Summary · context
Anoestrous Romney Marsh ewes with or without progesterone pretreatment were injected with multiple low-doses of gonadotrophin-releasing hormone followed by a single, larger bolus.
Summary · context
Ewes were slaughtered on day 3 or 5 after the bolus injection, and the ovaries were collected for histology and immunocytochemical examination for oxytocin-immunoreactivity.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0225760703

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 20:03 UTC
Study results updated
Version 1
9 Oct 2026, 02:52 UTC
First added · source update from Europe PMC

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