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Study · Animal study (in vivo) · mouse · 1990

5 results

Effect of thymic hormones on induction of experimental allergic encephalomyelitis in old mice.

Endoh M, Tabira T

The Tohoku journal of experimental medicine1 Aug 1990Cited by 3 (Europe PMC)

PMID2256103 (opens in a new tab)DOI10.1620/tjem.161.303 (opens in a new tab)PepBankPUB-02256103
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In young and old mice, tested thymic hormones, including FTS, had no significant effect on proliferative responses to PLP.

    In plain wordsIn mice, tested thymic hormones, including FTS, did not significantly change proliferation in response to PLP.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeIn vivo proliferation to PLP
    Study

    mousen: not reported in source

    Young and old mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymosin fraction 5 (TF-5) and serum thymic factor (FTS) had no significant in vitro and in vivo effect on proliferative responses to PLP and concanavalin A (Con A), and on EAE induction in young and old mice.
    1 context sentence
    Summary · context
    This study was aimed at restoring decreased T-cell functions and reduced susceptibility to proteolipid apoprotein (PLP) induced-experimental allergic encephalomyelitis (EAE) in old mice with thymic hormones.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In young and old mice, tested thymic hormones, including FTS, had no significant effect on proliferative responses to Con A.

    In plain wordsIn mice, tested thymic hormones, including FTS, did not significantly change proliferation in response to Con A.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeIn vivo proliferation to Con A
    Study

    mousen: not reported in source

    Young and old mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymosin fraction 5 (TF-5) and serum thymic factor (FTS) had no significant in vitro and in vivo effect on proliferative responses to PLP and concanavalin A (Con A), and on EAE induction in young and old mice.
    1 context sentence
    Summary · context
    This study was aimed at restoring decreased T-cell functions and reduced susceptibility to proteolipid apoprotein (PLP) induced-experimental allergic encephalomyelitis (EAE) in old mice with thymic hormones.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In young and old mice, tested thymic hormones, including FTS, had no significant effect on EAE induction.

    In plain wordsIn mice, tested thymic hormones, including FTS, did not significantly change experimental allergic encephalomyelitis induction.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeEAE induction
    Study

    mousen: not reported in source

    Young and old mice
    Outcome group
    Immune response · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymosin fraction 5 (TF-5) and serum thymic factor (FTS) had no significant in vitro and in vivo effect on proliferative responses to PLP and concanavalin A (Con A), and on EAE induction in young and old mice.
    1 context sentence
    Summary · context
    This study was aimed at restoring decreased T-cell functions and reduced susceptibility to proteolipid apoprotein (PLP) induced-experimental allergic encephalomyelitis (EAE) in old mice with thymic hormones.
  4. 04LabIn vitro (cells)Efficacy outcome

    In mouse cells, the tested thymic hormones, including FTS, had no significant effect on proliferative responses to PLP.

    In plain wordsIn cells from mice, tested thymic hormones, including FTS, did not significantly change proliferation in response to PLP.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeIn vitro proliferation to PLP
    Study

    mousen: not reported in source

    Young and old mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymosin fraction 5 (TF-5) and serum thymic factor (FTS) had no significant in vitro and in vivo effect on proliferative responses to PLP and concanavalin A (Con A), and on EAE induction in young and old mice.
    1 context sentence
    Summary · context
    This study was aimed at restoring decreased T-cell functions and reduced susceptibility to proteolipid apoprotein (PLP) induced-experimental allergic encephalomyelitis (EAE) in old mice with thymic hormones.
  5. 05LabIn vitro (cells)Efficacy outcome

    In mouse cells, the tested thymic hormones, including FTS, had no significant effect on proliferative responses to Con A.

    In plain wordsIn cells from mice, tested thymic hormones, including FTS, did not significantly change proliferation in response to Con A.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeIn vitro proliferation to Con A
    Study

    mousen: not reported in source

    Young and old mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymosin fraction 5 (TF-5) and serum thymic factor (FTS) had no significant in vitro and in vivo effect on proliferative responses to PLP and concanavalin A (Con A), and on EAE induction in young and old mice.
    1 context sentence
    Summary · context
    This study was aimed at restoring decreased T-cell functions and reduced susceptibility to proteolipid apoprotein (PLP) induced-experimental allergic encephalomyelitis (EAE) in old mice with thymic hormones.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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