In women after ovariectomy, distal radius bone mineral content did not change significantly during immediate salmon calcitonin treatment.
In plain wordsIn women after ovariectomy, forearm bone mineral content did not change significantly during immediate salmon calcitonin treatment.
- Peptide
- Calcitonin-salmon
- Outcome
- No significant changeDistal radius bone mineral content with immediate treatment
- Study
n: not reported in source
- Outcome group
- Bone and joint · Musculoskeletal
- Studied dose
- 100 MRC U every other day · intramuscular · 12 monthsAs given in this study (human).
Source sentences
After 12 months of study, no significant changes of BMC were observed in the 12 months sCT treated group, while control patients, treated 6 months after the ovariectomy, showed a significant decrease in BMC values.(ABSTRACT TRUNCATED AT 250 WORDS)
4 context sentences(design, population, supporting numbers)
We present the results of a 12-month clinical study assessing the effects of synthetic salmon calcitonin (sCT) on a group of fertile white women who had undergone ovariectomy for uterine fibromatosis.
The study consisted of an initial double-blind phase of 6 months, followed by a 6-month open period.
Treated patients were given 100 MRC U of synthetic salmon CT injected i.m. in the morning, every other day, starting on the 7th day after the operation and continued for 12 months.
Control patients received a placebo injection for the first 6 months; subsequently, they too were treated with sCT i.m. every other day for 6 months at the same dose as the 12 month-treated group.