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Study · Measured the body's own peptide · 1990

5 results

Immunohistochemical mapping of delta sleep-inducing peptide in the cat brain and hypophysis. Relationships with the LHRH system and corticotropes.

Charnay Y, Léger L, Golaz J, Sallanon M, Vallet PG, Guntern R, Bouras C, Constantinidis J, Jouvet M, Tissot R

Journal of chemical neuroanatomy1 Sept 1990Cited by 5 (Europe PMC)

PMID2222894 (opens in a new tab)PepBankPUB-02222894

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In the cat brain, DSIP-like immunoreactive cell bodies were mainly found in the diagonal band of Broca, ventral septum and anterior hypothalamic areas.

    In plain wordsIn cats, cell bodies with the body's own DSIP-like material were found mainly in the diagonal band of Broca, septum and hypothalamus.

    Outcome
    Not applicableDSIP-like immunoreactive cell bodies in cat brain
    Study

    catn: not reported in source

    Cat brain and hypophysis, indirect immunofluorescence
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Delta sleep-inducing peptide-like-immunoreactive cell bodies mostly visualized in colchicine-pretreated animals were mainly found scattered throughout the diagonal band of Broca, the ventral septum and the anterior hypothalamic areas.
    1 context sentence
    Summary · context
    Using the indirect immunofluorescence method, the distribution of the delta sleep-inducing peptide was studied in the cat brain and hypophysis.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In the cat brain, the heaviest concentrations of DSIP-like immunoreactive fibres were in the septo-preoptic region, median eminence and pituitary stalk.

    In plain wordsIn cats, nerve fibres with the body's own DSIP-like material were densest in the septo-preoptic region, median eminence and pituitary stalk.

    Outcome
    Not applicableDSIP-like immunoreactive fibres in cat brain
    Study

    catn: not reported in source

    Cat brain and hypophysis, indirect immunofluorescence
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    The heaviest concentrations of delta sleep-inducing peptide-like-immunoreactive varicose fibres and terminal-like structures were observed in the septo-preoptic region, in the median eminence and pituitary stalk.
    1 context sentence
    Summary · context
    Using the indirect immunofluorescence method, the distribution of the delta sleep-inducing peptide was studied in the cat brain and hypophysis.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In the cat brain, DSIP-like immunoreactivity frequently occurred in LHRH-immunoreactive neurons and vice versa.

    In plain wordsIn cats, the body's own DSIP-like material was often found in the same neurons as LHRH.

    Outcome
    Not applicableDSIP and LHRH colocalization
    Study

    catn: not reported in source

    Cat brain and hypophysis, indirect immunofluorescence
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Elution-restaining experiments revealed that delta sleep-inducing peptide-like immunoreactivity frequently occurred in luteinizing hormone-releasing hormone-immunoreactive neurons and vice versa.
    1 context sentence
    Summary · context
    Using the indirect immunofluorescence method, the distribution of the delta sleep-inducing peptide was studied in the cat brain and hypophysis.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In the cat pituitary, DSIP-like immunoreactivity was detected in most melanocorticotropes of the pars intermedia and in a large subpopulation of corticotropes of the pars distalis.

    In plain wordsIn cats, the body's own DSIP-like material was found in most melanocorticotropes and many corticotropes of the pituitary.

    Outcome
    Not applicableDSIP-like immunoreactivity in pituitary corticotropes
    Study

    catn: not reported in source

    Cat brain and hypophysis, indirect immunofluorescence
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    At the pituitary level, delta sleep-inducing peptide-like immunoreactivity was detected in most, if not all, melanocorticotropes of the pars intermedia and further in a large subpopulation of corticotropes mainly located in the zona tuberalis of the pars distalis.
    1 context sentence
    Summary · context
    Using the indirect immunofluorescence method, the distribution of the delta sleep-inducing peptide was studied in the cat brain and hypophysis.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  5. 05AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In the cat brain, few DSIP-immunoreactive fibres supplied the fimbria-fornix, the dorsal part of the subfornical organ, the medial habenular nucleus and the periaqueductal gray.

    In plain wordsIn cats, a few nerve fibres with the body's own DSIP-like material were found in several other brain regions.

    Outcome
    Not applicableDSIP-like immunoreactive fibres in other cat brain regions
    Study

    catn: not reported in source

    Cat brain and hypophysis, indirect immunofluorescence
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Some other brain regions supplied with few delta sleep-inducing peptide-immunoreactive fibres included the fimbria-fornix, the dorsal part of the subfornical organ, the medial habenular nucleus and more caudally, the periaqueductal gray.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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