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Study · Measured the body's own peptide · 1990

5 results

Sex differences among oxytocin-immunoreactive neuronal systems in the mouse hypothalamus.

Häussler HU, Jirikowski GF, Caldwell JD

Journal of chemical neuroanatomy1 Jul 1990Cited by 44 (Europe PMC)

PMID2204355 (opens in a new tab)PepBankPUB-02204355
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In mouse hypothalamus, the overall distribution of oxytocin neurons in the classical magnocellular nuclei was similar in males and females, with quantitative differences.

    In plain wordsIn mice, the body's own oxytocin nerve cells sat in similar places in males and females, but the numbers differed.

    Peptide
    Oxytocin
    Outcome
    No significant changeOverall topographical distribution of oxytocin neurons in the magnocellular nuclei
    Study

    mousen: not reported in source

    hypothalamic tissue from male and female mice
    Comparator
    Male versus female mice
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    While the overall topographical distribution of oxytocin neurons in the classical magnocellular nuclei was similar in both genders, quantitative differences could be observed.
    1 context sentence
    Summary · context
    Serial frontal sections of male and female mouse hypothalamus were immunostained with an antiserum to oxytocin, in order to study the topographical distribution of oxytocinergic perikarya and processes.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In mouse hypothalamus, female mice had far more oxytocin-immunostained perikarya than male mice.

    In plain wordsIn mice, females had far more nerve cell bodies with the body's own oxytocin in the hypothalamus than males.

    Peptide
    Oxytocin
    Outcome
    IncreaseNumber of oxytocin-immunostained perikarya
    Study

    mousen: not reported in source

    hypothalamic tissue from male and female mice
    Comparator
    Male mice
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    The numbers of immunostained perikarya and the amounts of oxytocin found in females exceeded by far the numbers and amounts found in males.
    1 context sentence
    Summary · context
    Serial frontal sections of male and female mouse hypothalamus were immunostained with an antiserum to oxytocin, in order to study the topographical distribution of oxytocinergic perikarya and processes.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In mouse hypothalamus, tissue from female mice contained far more oxytocin than tissue from male mice.

    In plain wordsIn mice, the hypothalamus of females held far more of the body's own oxytocin than that of males.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin content of hypothalamic tissue
    Study

    mousen: not reported in source

    hypothalamic tissue from male and female mice
    Comparator
    Male mice
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    The numbers of immunostained perikarya and the amounts of oxytocin found in females exceeded by far the numbers and amounts found in males.
    1 context sentence
    Summary · context
    Serial frontal sections of male and female mouse hypothalamus were immunostained with an antiserum to oxytocin, in order to study the topographical distribution of oxytocinergic perikarya and processes.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In mice, females had more oxytocin-immunostained axons projecting within the brain than males, especially in parts of the limbic system.

    In plain wordsIn mice, females had more nerve fibres with the body's own oxytocin inside the brain than males, mostly in the limbic system.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin-immunostained axons projecting within the brain
    Study

    mousen: not reported in source

    hypothalamic tissue from male and female mice
    Comparator
    Male mice
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Male mice had fewer oxytocin-immunostained axons, projecting within the brain, than females.
    2 context sentences
    Summary · context
    This was especially apparent in parts of the limbic system.
    Summary · context
    Serial frontal sections of male and female mouse hypothalamus were immunostained with an antiserum to oxytocin, in order to study the topographical distribution of oxytocinergic perikarya and processes.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  5. 05AnimalEndogenous levelAnimal study (in vivo)Other

    In male mice, oxytocin-immunostained neurons in the perifornical region, the lateral hypothalamus and the ventral ansa lenticularis were mostly absent.

    In plain wordsIn mice, males mostly lacked the body's own oxytocin nerve cells in three brain areas where females had them.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin-immunostained neurons in perifornical region, lateral hypothalamus and ventral ansa lenticularis
    Study

    mousen: not reported in source

    hypothalamic tissue from male and female mice
    Comparator
    Female mice
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Oxytocin-immunostained neurons in the perifornical region, the lateral hypothalamus and the ventral ansa lenticularis were mostly absent in males.
    1 context sentence
    Summary · context
    Serial frontal sections of male and female mouse hypothalamus were immunostained with an antiserum to oxytocin, in order to study the topographical distribution of oxytocinergic perikarya and processes.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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