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Study · Measured the body's own peptide · 1990

4 results

Distribution and colocalization of delta sleep-inducing peptide and luteinizing hormone-releasing hormone in the aged human brain: an immunohistochemical study.

Vallet PG, Charnay Y, Bouras C

Journal of chemical neuroanatomy1 May 1990Cited by 9 (Europe PMC)

PMID2194498 (opens in a new tab)PepBankPUB-02194498
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueOther

    In aged human brain sections, DSIP and LHRH immunoreactivities were often colocalized.

    In plain wordsIn human brain tissue, the body's own DSIP and LHRH were often found in the same cells.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableColocalization of DSIP and LHRH immunoreactivity
    Study

    humann: not reported in source

    Aged human brain tissue sections (immunofluorescence)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    With a modified elution technique, sequential stainings on the same section showed that DSIP- and LHRH-immunoreactivities were often colocalized.
    1 context sentence
    Summary · context
    The distributions of delta sleep-inducing peptide (DSIP)- and luteinizing hormone-releasing hormone (LHRH)-immunoreactive neurons were investigated in the human brain with special emphasis on the basal forebrain (from the septum to the hypothalamus), using indirect immunofluorescence.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueOther

    In aged human brain, small numbers of LHRH/DSIP-immunoreactive cells were detected in the diagonal band of Broca, the medial septum and the ventral hypothalamus.

    In plain wordsIn human brain tissue, a few cells with natural DSIP and LHRH were seen in the diagonal band of Broca, medial septum and ventral hypothalamus.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDistribution of LHRH/DSIP-immunoreactive cells
    Study

    humann: not reported in source

    Aged human brain tissue sections (immunofluorescence)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Small numbers of LHRH/DSIP-immunoreactive cells were essentially detected in the diagonal band of Broca, the medial septum and the ventral hypothalamus.
    1 context sentence
    Summary · context
    The distributions of delta sleep-inducing peptide (DSIP)- and luteinizing hormone-releasing hormone (LHRH)-immunoreactive neurons were investigated in the human brain with special emphasis on the basal forebrain (from the septum to the hypothalamus), using indirect immunofluorescence.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelEx vivo tissueOther

    In aged human brain, the richest areas with fibres and terminal-like structures were the preoptic area, ventromedial and ventrolateral hypothalamic areas, periventricular region and certain circumventricular organs.

    In plain wordsIn human brain tissue, natural DSIP-related fibres were most dense in the preoptic area and hypothalamus regions.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDistribution of DSIP-immunoreactive fibres and terminals
    Study

    humann: not reported in source

    Aged human brain tissue sections (immunofluorescence)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    The richest areas displaying fibres and terminal-like structures were the preoptic area, the ventromedial and ventrolateral hypothalamic areas, the periventricular region and certain circumventricular organs (i.e. median eminence, vascular organ of the lamina terminalis).
    1 context sentence
    Summary · context
    The distributions of delta sleep-inducing peptide (DSIP)- and luteinizing hormone-releasing hormone (LHRH)-immunoreactive neurons were investigated in the human brain with special emphasis on the basal forebrain (from the septum to the hypothalamus), using indirect immunofluorescence.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  4. 04LabEndogenous levelEx vivo tissueOther

    In aged human brain, few isolated fibres were observed in the subfornical organ.

    In plain wordsIn human brain tissue, only a few natural DSIP-related fibres were seen in the subfornical organ.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-immunoreactive fibres in subfornical organ
    Study

    humann: not reported in source

    Aged human brain tissue sections (immunofluorescence)
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Few isolated fibres were observed in the subfornical organ.
    1 context sentence
    Summary · context
    The distributions of delta sleep-inducing peptide (DSIP)- and luteinizing hormone-releasing hormone (LHRH)-immunoreactive neurons were investigated in the human brain with special emphasis on the basal forebrain (from the septum to the hypothalamus), using indirect immunofluorescence.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

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