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Study · Animal study (in vivo) · mouse · 1990

4 results

Serum thymic factor as a radioprotective agent promoting survival after X-irradiation.

Kobayashi H, Abe H, Awaya A, Inano H, Shikita M

Experientia1 May 1990Cited by 3 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In irradiated mice, serum thymic factor protected against death.

    In plain wordsIn mice, serum thymic factor protected against death after whole-body irradiation.

    Outcome
    DecreaseDeath after irradiation
    Study

    mousen: not reported in source

    Whole-body X-irradiation
    Outcome group
    Mortality · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Serum thymic factor (FTS, zinc-free thymulin) protected mice from death after whole-body X-irradiation.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In irradiated mice, serum thymic factor was significantly radioprotective when administered after irradiation.

    In plain wordsIn mice, serum thymic factor protected against radiation when given after irradiation.

    Outcome
    IncreaseRadioprotection after irradiation
    Study

    mousen: not reported in source

    Whole-body X-irradiation
    Outcome group
    Mortality · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It was significantly radioprotective even when administered after irradiation, but it was more effective when administered both before and after irradiation.
    1 context sentence
    Summary · context
    Serum thymic factor (FTS, zinc-free thymulin) protected mice from death after whole-body X-irradiation.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In mice, serum thymic factor was more radioprotective before and after irradiation than after irradiation only.

    In plain wordsIn mice, serum thymic factor protected more when given before and after irradiation than after irradiation only.

    Outcome
    IncreaseRadioprotection by administration schedule
    Study

    mousen: not reported in source

    Whole-body X-irradiation
    Comparator
    Administration after irradiation only
    Outcome group
    Mortality · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It was significantly radioprotective even when administered after irradiation, but it was more effective when administered both before and after irradiation.
    1 context sentence
    Summary · context
    Serum thymic factor (FTS, zinc-free thymulin) protected mice from death after whole-body X-irradiation.
  4. 04AnimalAnimal study (in vivo)Mechanism

    In irradiated mice, serum thymic factor protection appeared to involve enhanced hematologic recovery.

    In plain wordsIn mice, serum thymic factor protection appeared to involve better blood cell recovery after irradiation.

    Outcome
    IncreaseHematologic recovery
    Study

    mousen: not reported in source

    Whole-body X-irradiation
    Outcome group
    Immune response · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The protective effect appears to be due to the enhancement of hematologic recovery in the animals.
    1 context sentence
    Summary · context
    Serum thymic factor (FTS, zinc-free thymulin) protected mice from death after whole-body X-irradiation.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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