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Study · Measured the body's own peptide · 1990

3 results

The vasopressin and oxytocin content in the neurohypophysis under conditions of increased beta-adrenergic transmission in euhydrated and dehydrated rats.

Janus J, Guzek JW

Experimental and clinical endocrinology1 Aug 1990Cited by 1 (Europe PMC)

PMID2174001 (opens in a new tab)DOI10.1055/s-0029-1210968 (opens in a new tab)PepBankPUB-02174001
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, the neurohypophysial oxytocic activity (a measure of the body's own oxytocin) diminished progressively during water deprivation.

    In plain wordsIn rats, the body's own oxytocin activity in the pituitary gland fell step by step while the rats had no water.

    Peptide
    Oxytocin
    Outcome
    DecreaseNeurohypophysial oxytocic activity during water deprivation
    Study

    ratn: not reported in source

    in vivo, rat neurohypophysis
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    The neurohypophysial vasopressor and oxytocic activity diminished progressively during deprivation of water.
    2 context sentences
    Summary · context
    In rats euhydrated or dehydrated for two or four days the neurohypophysial vasopressin and oxytocin content was estimated.
    Summary · context
    Rats were given intracerebroventricularly (i.c.v.) isoprenaline in a daily dose of 10 micrograms dissolved in 10 microliters of 0.9% sodium chloride.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, a single dose of isoprenaline diminished the neurohypophysial oxytocin storage.

    In plain wordsIn rats, one dose of isoprenaline lowered the body's own oxytocin stored in the pituitary gland.

    Peptide
    Oxytocin
    Outcome
    DecreaseNeurohypophysial oxytocin content after a single dose of isoprenaline
    Study

    ratn: not reported in source

    in vivo, rat neurohypophysis
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    The neurohypophysial oxytocin storage was diminished by a single dose of isoprenaline
    2 context sentences
    Summary · context
    In rats euhydrated or dehydrated for two or four days the neurohypophysial vasopressin and oxytocin content was estimated.
    Summary · context
    Rats were given intracerebroventricularly (i.c.v.) isoprenaline in a daily dose of 10 micrograms dissolved in 10 microliters of 0.9% sodium chloride.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In dehydrated rats, isoprenaline distinctly intensified the depletion of neurohypophysial oxytocin.

    In plain wordsIn dehydrated rats, isoprenaline made the loss of the body's own oxytocin from the pituitary gland clearly larger.

    Peptide
    Oxytocin
    Outcome
    DecreaseNeurohypophysial oxytocin depletion with isoprenaline during dehydration
    Study

    ratn: not reported in source

    in vivo, rat neurohypophysis
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    on the contrary, during dehydration isoprenaline distinctly intensified the oxytocin depletion in the neurohypophysis.
    2 context sentences
    Summary · context
    In rats euhydrated or dehydrated for two or four days the neurohypophysial vasopressin and oxytocin content was estimated.
    Summary · context
    Rats were given intracerebroventricularly (i.c.v.) isoprenaline in a daily dose of 10 micrograms dissolved in 10 microliters of 0.9% sodium chloride.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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