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Study · Animal study (in vivo) · rat · 1990

2 results

The plasma pattern of growth hormone in conscious rats during late pregnancy.

Carlsson L, Edén S, Jansson JO

The Journal of endocrinology1 Feb 1990Cited by 11 (Europe PMC)

PMID2138207 (opens in a new tab)DOI10.1677/joe.0.1240191 (opens in a new tab)PepBankPUB-02138207
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In conscious pregnant rats on day 18 of gestation, repeated intravenous infusions of human GRF(1-29)-NH2 analogue consistently produced GH responses.

    In plain wordsIn pregnant rats, repeated doses of a GH-releasing factor analogue reliably triggered growth hormone release.

    Peptide
    Sermorelin
    Outcome
    IncreaseGH response to repeated hGRF(1-29)-NH2 infusions on day 18 of gestation
    Study

    ratn: not reported in source

    Conscious pregnant female rats
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    1 microgram · intravenousAs given in this study (rat).

    Source sentences

    Summary
    Pregnant females consistently responded to multiple i.v. infusions of 1 microgram human GH-releasing factor analogue (hGRF(1-29)-NH2) given at 45-min intervals on day 18 of gestation.
    1 context sentence
    Summary · context
    The plasma GH levels of female rats during late pregnancy were determined using an automatic method for repetitive blood sampling from conscious animals.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In pregnant rats, GRF analogue-stimulated plasma GH levels were undetectable after hypophysectomy.

    In plain wordsIn pregnant rats with the pituitary gland removed, the GH-releasing factor analogue produced no detectable growth hormone.

    Peptide
    Sermorelin
    Outcome
    No significant changeGRF analogue-stimulated plasma GH after hypophysectomy
    Study

    ratn: not reported in source

    Conscious pregnant female rats
    Comparator
    Pregnant rats before hypophysectomy
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    1 microgram · intravenousAs given in this study (rat).

    Source sentences

    Summary
    Both basal and GRF analogue-stimulated plasma GH levels were undetectable after hypophysectomy of pregnant rats.
    1 context sentence
    Summary · context
    The plasma GH levels of female rats during late pregnancy were determined using an automatic method for repetitive blood sampling from conscious animals.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 19:08 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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