In women with endometriosis, nafarelin and danazol produced comparable decreases in American Fertility Society scores.
In plain wordsIn women with endometriosis, nafarelin and danazol reduced disease scores similarly.
- Peptide
- Nafarelin
- Outcome
- Direction not reportedAmerican Fertility Society endometriosis score
- Study
n = 194
- Comparator
- Danazol 200 mg twice daily
- Outcome group
- Organ injury · Reproductive and sexual health
- Studied dose
- 200 micrograms twice daily · 6 monthsAs given in this study (human).
Source sentences
A comparison of decreases in both groups of American Fertility Society endometriosis scores and in severity scores developed by the investigators indicates that nafarelin and danazol are equally effective in the treatment of endometriosis.
4 context sentences(design, population, supporting numbers)
A double-blind, double-dummy, 6-month multicenter study comparing the effects of nafarelin and danazol in the treatment of endometriosis was completed recently by investigators from 13 institutions in seven European countries.
The 194 patients (aged 18 to 45 years) selected for the study were divided into two groups.
One group received nafarelin, 200 micrograms twice daily, and placebo capsules identical to danazol, twice daily.
The other group received danazol capsules, 200 mg twice daily, and a placebo nasal spray identical to nafarelin, twice daily.