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Study · Measured the body's own peptide · 1990

2 results

Prolactin-releasing factor: cellular origin in the intermediate lobe of the pituitary.

Laudon M, Grossman DA, Ben-Jonathan N

Endocrinology1 Jun 1990Cited by 22 (Europe PMC)

PMID2112457 (opens in a new tab)DOI10.1210/endo-126-6-3185 (opens in a new tab)PepBankPUB-02112457
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueOther

    In rat posterior pituitary, 90% of the total body's own oxytocin was localized in the neural lobe.

    In plain wordsIn rats, most of the pituitary's natural oxytocin sat in the neural lobe.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin distribution in posterior pituitary lobes
    Study

    ratn: not reported in source

    posterior pituitary lobes
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Measurements

    Share of total oxytocin in neural lobe
    90%
    posterior pituitary

    Source sentences

    Summary
    the localization of 90% of the total oxytocin in the neural lobe and 95% of alpha MSH in the intermediate lobe.
    1 context sentence
    Summary · context
    Posterior pituitaries from adult male rats were dispersed with trypsin and cultured for 1-7 days.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelIn vitro (cells)Other

    In cultured rat posterior pituitary cells, the cell content of the body's own oxytocin fell to under 5% of the original value within 1 week.

    In plain wordsIn rat pituitary cells grown in a dish, natural oxytocin fell to under 5% of the starting level within a week.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin content of cultured posterior pituitary cells
    Study

    ratn: not reported in source

    cultured posterior pituitary cells
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Both oxytocin and dopamine, two neuronal markers, were reduced to less than 5% of their original values within 1 week of cell culture.
    1 context sentence
    Summary · context
    Posterior pituitaries from adult male rats were dispersed with trypsin and cultured for 1-7 days.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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