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Study · Randomized controlled trial · n = 16 · 1990

4 results

Cotreatment with human growth hormone and gonadotropins for induction of ovulation: a controlled clinical trial.

Homburg R, West C, Torresani T, Jacobs HS

Fertility and sterility1 Feb 1990Cited by 102 (Europe PMC)

PMID2105243 (opens in a new tab)DOI10.1016/s0015-0282(16)53277-4 (opens in a new tab)PepBankPUB-02105243
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In women with anovulatory infertility, GH reduced the required hMG dose versus hMG plus placebo.

    In plain wordsIn women with infertility, GH reduced the required hMG dose versus hMG plus placebo.

    Peptide
    HGH (somatotropin)
    Outcome
    DecreaseRequired hMG dose
    Study

    n = 16

    Comparator
    hMG plus placebo
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    24 IU on alternate days, total dose 144 IUAs given in this study (human).

    Source sentences

    Summary
    On cotreatment with GH compared with placebo, there was a significant reduction in the required dose of hMG, duration of treatment, and the daily effective dose of gonadotropins.
    2 context sentences
    Summary · context
    A randomized, double-blind, placebo-controlled trial of cotreatment with biosynthetic, human sequence, growth hormone (GH), and human menopausal gonadotropins (hMG) for induction of ovulation was performed in 16 women with amenorrhea and anovulatory infertility.
    Summary · context
    Patients were randomly allocated to treatment with hMG + GH (24 IU on alternate days, total dose 144 IU) or hMG + placebo.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In women with anovulatory infertility, GH reduced treatment duration versus hMG plus placebo.

    In plain wordsIn women with infertility, GH reduced treatment duration versus hMG plus placebo.

    Peptide
    HGH (somatotropin)
    Outcome
    DecreaseTreatment duration
    Study

    n = 16

    Comparator
    hMG plus placebo
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    24 IU on alternate days, total dose 144 IUAs given in this study (human).

    Source sentences

    Summary
    On cotreatment with GH compared with placebo, there was a significant reduction in the required dose of hMG, duration of treatment, and the daily effective dose of gonadotropins.
    2 context sentences
    Summary · context
    A randomized, double-blind, placebo-controlled trial of cotreatment with biosynthetic, human sequence, growth hormone (GH), and human menopausal gonadotropins (hMG) for induction of ovulation was performed in 16 women with amenorrhea and anovulatory infertility.
    Summary · context
    Patients were randomly allocated to treatment with hMG + GH (24 IU on alternate days, total dose 144 IU) or hMG + placebo.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In women with anovulatory infertility, GH reduced the daily effective gonadotropin dose versus hMG plus placebo.

    In plain wordsIn women with infertility, GH reduced the daily effective gonadotropin dose versus hMG plus placebo.

    Peptide
    HGH (somatotropin)
    Outcome
    DecreaseDaily effective gonadotropin dose
    Study

    n = 16

    Comparator
    hMG plus placebo
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    24 IU on alternate days, total dose 144 IUAs given in this study (human).

    Source sentences

    Summary
    On cotreatment with GH compared with placebo, there was a significant reduction in the required dose of hMG, duration of treatment, and the daily effective dose of gonadotropins.
    2 context sentences
    Summary · context
    A randomized, double-blind, placebo-controlled trial of cotreatment with biosynthetic, human sequence, growth hormone (GH), and human menopausal gonadotropins (hMG) for induction of ovulation was performed in 16 women with amenorrhea and anovulatory infertility.
    Summary · context
    Patients were randomly allocated to treatment with hMG + GH (24 IU on alternate days, total dose 144 IU) or hMG + placebo.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In women with anovulatory infertility, IGF-I rose with GH but not placebo during hMG treatment.

    In plain wordsIn women with infertility, IGF-I rose with GH but not placebo during hMG treatment.

    Peptide
    HGH (somatotropin)
    Outcome
    IncreaseSerum IGF-I
    Study

    n = 16

    Comparator
    hMG plus placebo
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    24 IU on alternate days, total dose 144 IUAs given in this study (human).

    Source sentences

    Summary
    Serum insulin-like growth factor-I (IGF-I) rose during treatment with GH but not with placebo.
    2 context sentences
    Summary · context
    A randomized, double-blind, placebo-controlled trial of cotreatment with biosynthetic, human sequence, growth hormone (GH), and human menopausal gonadotropins (hMG) for induction of ovulation was performed in 16 women with amenorrhea and anovulatory infertility.
    Summary · context
    Patients were randomly allocated to treatment with hMG + GH (24 IU on alternate days, total dose 144 IU) or hMG + placebo.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:37 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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