In MCF-7 breast cancer cells grown in TA1-free media, thymosin alpha one was detected in culture supernatants and cytosol by RP-HPLC and radioimmunoassay.
In plain wordsIn breast cancer cells in a dish, the cells made their own thymosin alpha one, found in the culture fluid and cell contents.
- Peptide
- Thymosin alpha-1
- Outcome
- Not applicableTA1 detected in MCF-7 culture supernatants and cytosol
- Study
humann: not reported in source
MCF-7 breast cancer cells- Outcome group
- Tumor growth · Cancer
Source sentences
In a search to identify polypeptide growth factors for MCF-7 breast cancer cells we have detected the thymic hormone, thymosin alpha one (TA1) in culture supernatants and cytosol preparations of MCF-7 cells grown in TA1 free media. TA1 was identified by reverse phase-high performance liquid chromato…
1 context sentence(design, population, supporting numbers)
The growth of the human breast cancer cell line MCF-7 is stimulated in vitro by estradiol which has been shown to induce the release of numerous polypeptide growth factors into the culture media.
This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.