Skip to content

Study · Not a test of the peptide alone · 1991

3 results

[Modulation of the circadian rhythm of the glucocorticoid hormone level in mice by thymoptin administration at various times of day].

Shurlygina AV, Letiagin AIu, Chesnokova VM, Trufakin VA

Problemy endokrinologii1 Jan 1991Cited by 1 (Europe PMC)

PMID2027873 (opens in a new tab)PepBankPUB-02027873

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 01AnimalNot a test of Thymosin alpha-1 aloneAnimal study (in vivo)Efficacy outcome

    In male CBA mice, administration of thymopthin (a drug with 1% thymosin alpha‑1) changed the circadian rhythm of plasma corticosterone.

    In plain wordsIn mice, a drug containing a little thymosin alpha‑1 changed the daily rhythm of a stress hormone.

    Outcome
    MixedCircadian rhythm of plasma corticosterone
    Study

    mousen: not reported in source

    Comparator
    Physiological salt solution
    Outcome group
    Stress hormones · Endocrine and hormones

    Source sentences

    Summary
    Thymopthin administration was shown to result in change of circadian rhythm of the level of corticosteroids in mouse plasma.
    1 context sentence
    Summary · context
    The object of investigation was blood plasma of CBA male mice aged 12-16 weeks.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  2. 02AnimalNot a test of Thymosin alpha-1 aloneAnimal study (in vivo)Efficacy outcome

    In male CBA mice, morning administration of thymopthin (a drug with 1% thymosin alpha‑1) raised the daily plasma corticosterone concentration versus saline.

    In plain wordsIn mice, a drug containing a little thymosin alpha‑1 given in the morning raised a stress hormone more than saline.

    Outcome
    IncreaseDaily corticosterone concentration after morning administration
    Study

    mousen: not reported in source

    Comparator
    Physiological salt solution
    Outcome group
    Stress hormones · Endocrine and hormones

    Source sentences

    Summary
    Drug administration in the morning elevated daily concentration of corticosterone
    1 context sentence
    Summary · context
    The object of investigation was blood plasma of CBA male mice aged 12-16 weeks.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  3. 03AnimalNot a test of Thymosin alpha-1 aloneAnimal study (in vivo)Efficacy outcome

    In male CBA mice, evening administration of thymopthin (a drug with 1% thymosin alpha‑1) reduced the daily plasma corticosterone concentration versus saline.

    In plain wordsIn mice, a drug containing a little thymosin alpha‑1 given in the evening lowered a stress hormone compared with saline.

    Outcome
    DecreaseDaily corticosterone concentration after evening administration
    Study

    mousen: not reported in source

    Comparator
    Physiological salt solution
    Outcome group
    Stress hormones · Endocrine and hormones

    Source sentences

    Summary
    that also evening reduced it as compared to the control group that in the received the same volume of physiological salt solution.
    1 context sentence
    Summary · context
    The object of investigation was blood plasma of CBA male mice aged 12-16 weeks.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.