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Study · Not a test of the peptide alone · 1990

3 results

A glucagon-secretin-like peptide stimulates the intrinsic nervous plexus of guinea pig gallbladder.

Greco AV, Mancinelli R, Mingrone G, Racanicchi C

Experientia1 May 1990

PMID1971797 (opens in a new tab)DOI10.1007/bf01954226 (opens in a new tab)PepBankPUB-01971797
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Sermorelin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Sermorelin.

  1. 01LabNot a test of Sermorelin aloneEx vivo tissueMechanism

    In guinea pig gallbladder, the GRF-(1-29) analog (N-Ac-Tyr1, D-Phe2)-GRF-(1-29)-NH2 greatly increased the amplitude of spontaneous contractile waves.

    In plain wordsIn guinea pig gallbladder tissue, a GRF analog greatly increased the strength of spontaneous contraction waves.

    Peptide
    Sermorelin
    Outcome
    IncreaseGallbladder wave amplitude
    Study

    guinea pign: not reported in source

    gallbladder, spontaneous contractile activity
    Outcome group
    Gastrointestinal motility · Gastrointestinal

    Source sentences

    Summary
    (N-Ac-Tyr1, D-Phe2)-GRF-(1-29)-NH2, (14-GRF analog), which is known to stimulate digestive enzyme secretion by interacting with the VIP-preferring receptors, greatly increased the amplitude and frequency of waves as well as the muscular tone.
    1 context sentence
    Summary · context
    The role of vasoactive intestinal peptide (VIP), as a possible neurotransmitter of the intrinsic nerve plexus in the guinea pig gallbladder, was investigated by monitoring spontaneous contractile activity.

    In this study, Sermorelin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Sermorelin.

  2. 02LabNot a test of Sermorelin aloneEx vivo tissueMechanism

    In guinea pig gallbladder, the GRF-(1-29) analog (N-Ac-Tyr1, D-Phe2)-GRF-(1-29)-NH2 greatly increased the frequency of spontaneous contractile waves.

    In plain wordsIn guinea pig gallbladder tissue, a GRF analog greatly increased how often spontaneous contraction waves occurred.

    Peptide
    Sermorelin
    Outcome
    IncreaseGallbladder wave frequency
    Study

    guinea pign: not reported in source

    gallbladder, spontaneous contractile activity
    Outcome group
    Gastrointestinal motility · Gastrointestinal

    Source sentences

    Summary
    (N-Ac-Tyr1, D-Phe2)-GRF-(1-29)-NH2, (14-GRF analog), which is known to stimulate digestive enzyme secretion by interacting with the VIP-preferring receptors, greatly increased the amplitude and frequency of waves as well as the muscular tone.
    1 context sentence
    Summary · context
    The role of vasoactive intestinal peptide (VIP), as a possible neurotransmitter of the intrinsic nerve plexus in the guinea pig gallbladder, was investigated by monitoring spontaneous contractile activity.

    In this study, Sermorelin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Sermorelin.

  3. 03LabNot a test of Sermorelin aloneEx vivo tissueMechanism

    In guinea pig gallbladder, the GRF-(1-29) analog (N-Ac-Tyr1, D-Phe2)-GRF-(1-29)-NH2 greatly increased muscular tone.

    In plain wordsIn guinea pig gallbladder tissue, a GRF analog greatly increased muscle tone.

    Peptide
    Sermorelin
    Outcome
    IncreaseGallbladder muscular tone
    Study

    guinea pign: not reported in source

    gallbladder, spontaneous contractile activity
    Outcome group
    Gastrointestinal motility · Gastrointestinal

    Source sentences

    Summary
    (N-Ac-Tyr1, D-Phe2)-GRF-(1-29)-NH2, (14-GRF analog), which is known to stimulate digestive enzyme secretion by interacting with the VIP-preferring receptors, greatly increased the amplitude and frequency of waves as well as the muscular tone.
    1 context sentence
    Summary · context
    The role of vasoactive intestinal peptide (VIP), as a possible neurotransmitter of the intrinsic nerve plexus in the guinea pig gallbladder, was investigated by monitoring spontaneous contractile activity.

    In this study, Sermorelin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Sermorelin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 10:21 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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