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Study · Animal study (in vivo) · rat · 1990

2 results

[Bombesin, dermorphin, physalaemin and sauvagine: effects on superficial and depth EEG tracings in epileptic and non-epileptic rats].

de Romanis F, Sopranzi N

La Clinica terapeutica1 Apr 1990

PMID1971781 (opens in a new tab)PepBankPUB-01971781
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In non-epileptic rats, dermorphin produced slow brain electrical activity.

    In plain wordsIn rats without epilepsy, dermorphin produced slow brain electrical activity.

    Peptide
    Dermorphin
    Outcome
    IncreaseSlow brain electrical activity
    Study

    ratn: not reported in source

    Non-epileptic and epileptic rats
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    All the other peptides gave rise to slow activity with different duration.
    2 context sentences
    Summary · context
    On the normal electrical background activity of rat brain only physalaemin had no effect.
    Summary · context
    These peptides were administered to non-epileptic and epileptic rats: SEEG and DEEG were recorded.
  2. 02AnimalAnimal study (in vivo)Activity measurement

    In epileptic rats, dermorphin blocked metrazol action at its onset.

    In plain wordsIn rats with epilepsy, dermorphin blocked metrazol action at its onset.

    Peptide
    Dermorphin
    Outcome
    DecreaseMetrazol-induced epileptic activity
    Study

    ratn: not reported in source

    Non-epileptic and epileptic rats
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    bombesin seemed to strengthen the action of metrazol and dermorphin blocked it at the onset.
    1 context sentence
    Summary · context
    These peptides were administered to non-epileptic and epileptic rats: SEEG and DEEG were recorded.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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