In guinea-pigs, injections of [Nle27]-GRF(1-29)NH2 released GH in a dose-dependent way.
In plain wordsIn guinea-pigs, injected GH-releasing factor caused more growth hormone release at higher doses.
- Peptide
- Sermorelin
- Outcome
- IncreaseGH release after [Nle27]-GRF(1-29)NH2 injection
- Study
guinea pign: not reported in source
Guinea-pig- Outcome group
- Growth hormone and IGF-1 · Endocrine and hormones
- Studied dose
- 2, 10 or 20 microgramsAs given in this study (guinea pig).
Source sentences
GH was released in response to GH-releasing factor (GRF) injections (2, 10 or 20 micrograms [Nle27]-GRF(1-29)NH2) in a dose-dependent fashion
1 context sentence(design, population, supporting numbers)
We have identified guinea-pig GH, established a sensitive heterologous radioimmunoassay and adapted our automatic blood microsampling method to study spontaneous GH secretion in this species.