In athymic mice with human endometrial carcinoma, enclomiphene supported tumor growth as actively as tamoxifen.
In plain wordsIn mice with human endometrial tumors, enclomiphene supported tumor growth as strongly as tamoxifen.
- Peptide
- Enclomiphene
- Outcome
- Direction not reportedEndometrial tumor growth stimulation
- Study
mousen: not reported in source
athymic mice with human EnCa101 endometrial carcinoma- Comparator
- tamoxifen
- Outcome group
- Tumor growth · Cancer
- Studied dose
- Dose not stated
Source sentences
Trioxifene, enclomiphene and nafoxidine are all as active as tamoxifen whereas the antiestrogen keoxifene, that has reduced estrogen-like properties, will partially inhibit tamoxifen-stimulated growth.
2 context sentences(design, population, supporting numbers)
An estrogen receptor and progesterone receptor positive endometrial carcinoma (EnCa101) will grow in response to either estradiol or tamoxifen when transplanted into athymic mice.
We have tested several antiestrogens with different properties to determine their ability to support endometrial tumor growth.