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Study · Animal study (in vivo) · rat · 1991

5 results

Oxytocin selectively increases holding and licking of neonates in preweanling but not postweanling juvenile rats.

Peterson G, Mason GA, Barakat AS, Pedersen CA

Behavioral neuroscience1 Jun 1991Cited by 5 (Europe PMC)

PMID1863367 (opens in a new tab)DOI10.1037//0735-7044.105.3.470 (opens in a new tab)PepBankPUB-01863367
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In preweanling juvenile rats, intracisternal oxytocin significantly increased active holding of pups compared with saline and no treatment.

    In plain wordsIn young rats before weaning, oxytocin made them hold pups more than saline or no treatment did.

    Peptide
    Oxytocin
    Outcome
    IncreaseActive holding of pups in preweanling juvenile rats
    Study

    ratn: not reported in source

    Comparator
    Saline and no treatment
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    2 micrograms · intracisternalAs given in this study (rat).

    Source sentences

    Summary
    Compared with saline and no treatment, OXT significantly increased active holding of pups in preweanling but not postweanling juvenile rats.
    1 context sentence
    Summary · context
    The effects of intracisternal (IC) administration of OXT (2 micrograms) on pup-directed and other behaviors in preweanling and postweanling juvenile rats were tested.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In postweanling juvenile rats, intracisternal oxytocin did not significantly increase active holding of pups compared with saline and no treatment.

    In plain wordsIn young rats after weaning, oxytocin did not make them hold pups more than saline or no treatment did.

    Peptide
    Oxytocin
    Outcome
    No significant changeActive holding of pups in postweanling juvenile rats
    Study

    ratn: not reported in source

    Comparator
    Saline and no treatment
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    2 micrograms · intracisternalAs given in this study (rat).

    Source sentences

    Summary
    Compared with saline and no treatment, OXT significantly increased active holding of pups in preweanling but not postweanling juvenile rats.
    1 context sentence
    Summary · context
    The effects of intracisternal (IC) administration of OXT (2 micrograms) on pup-directed and other behaviors in preweanling and postweanling juvenile rats were tested.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In juvenile rats, intracisternal oxytocin did not stimulate other components of adultlike maternal behavior.

    In plain wordsIn young rats, oxytocin did not trigger other parts of adult-like maternal behavior.

    Peptide
    Oxytocin
    Outcome
    No significant changeOther components of adultlike maternal behavior
    Study

    ratn: not reported in source

    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    2 micrograms · intracisternalAs given in this study (rat).

    Source sentences

    Summary
    No other components of adultlike MB were stimulated by OXT.
    1 context sentence
    Summary · context
    The effects of intracisternal (IC) administration of OXT (2 micrograms) on pup-directed and other behaviors in preweanling and postweanling juvenile rats were tested.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In juvenile rats, intracisternal oxytocin decreased inactive touching of pups.

    In plain wordsIn young rats, oxytocin reduced passive touching of pups.

    Peptide
    Oxytocin
    Outcome
    DecreaseInactive touching of pups
    Study

    ratn: not reported in source

    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    2 micrograms · intracisternalAs given in this study (rat).

    Source sentences

    Summary
    decreased inactive touching of pups
    1 context sentence
    Summary · context
    The effects of intracisternal (IC) administration of OXT (2 micrograms) on pup-directed and other behaviors in preweanling and postweanling juvenile rats were tested.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In juvenile rats of all ages tested, intracisternal oxytocin robustly increased self-grooming.

    In plain wordsIn young rats of all ages tested, oxytocin strongly increased self-grooming.

    Peptide
    Oxytocin
    Outcome
    IncreaseSelf-grooming
    Study

    ratn: not reported in source

    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    2 micrograms · intracisternalAs given in this study (rat).

    Source sentences

    Summary
    robustly increased selfgrooming in juveniles at all ages tested.
    1 context sentence
    Summary · context
    The effects of intracisternal (IC) administration of OXT (2 micrograms) on pup-directed and other behaviors in preweanling and postweanling juvenile rats were tested.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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