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Study · Measured the body's own peptide · 1991

3 results

Immunocytochemical demonstration of DSIP-like immunoreactivity in the hypothalamus of the rat.

Skagerberg G, Bjartell A, Vallet PG, Charnay Y

Peptides1 Sept 1991Cited by 4 (Europe PMC)

PMID1800953 (opens in a new tab)DOI10.1016/0196-9781(91)90074-y (opens in a new tab)PepBankPUB-01800953
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In the rat mediobasal hypothalamus, varicose nerve fibres showed the body's own DSIP immunoreactivity, mostly in the arcuate nucleus, median eminence and pituitary stalk.

    In plain wordsIn rats, nerve fibres in the hypothalamus carried the body's own DSIP, mostly in the arcuate nucleus and median eminence.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-IR nerve fibres in mediobasal hypothalamus
    Study

    ratn: not reported in source

    Rat diencephalon, immunocytochemistry
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Varicose nerve fibers exhibiting DSIP-IR were found throughout the mediobasal hypothalamus, most frequently in the hypothalamic arcuate nucleus and in the adjoining median eminence and pituitary stalk.
    1 context sentence
    Summary · context
    The distribution of delta sleep-inducing peptide immunoreactivity (DSIP-IR) was studied in the rat diencephalon.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In the rat hypothalamus, DSIP immunoreactive nerve fibres were also seen near the third ventricle and within the mamillary complex.

    In plain wordsIn rats, the body's own DSIP was also found in nerve fibres near the third ventricle and in the mamillary complex.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-IR innervation near third ventricle and mamillary complex
    Study

    ratn: not reported in source

    Rat diencephalon, immunocytochemistry
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    In the hypothalamus, DSIP-IR innervation was also observed close to the third ventricle and within the mamillary complex.
    1 context sentence
    Summary · context
    The distribution of delta sleep-inducing peptide immunoreactivity (DSIP-IR) was studied in the rat diencephalon.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In the rat hypothalamus, no cell bodies with DSIP immunoreactivity were found, even after colchicine pretreatment.

    In plain wordsIn rats, no cell bodies carrying the body's own DSIP were found in the hypothalamus, even after colchicine.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeDSIP-IR cell bodies
    Study

    ratn: not reported in source

    Rat diencephalon, immunocytochemistry
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Despite pretreatment with colchicine, no evidence of immunoreactive cell bodies containing DSIP-IR could be found.
    1 context sentence
    Summary · context
    The distribution of delta sleep-inducing peptide immunoreactivity (DSIP-IR) was studied in the rat diencephalon.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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