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Study · Measured the body's own peptide · 1991

5 results

Human pheochromocytoma cells studied in culture contain large amounts of DSIP-like material.

Nilsson O, Wängberg B, Wigander A, Lundmark K, Dahlström A, Ahlman H, Bjartell A, Ekman R

Peptides1 Sept 1991Cited by 4 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueOther

    In nine human pheochromocytoma tumors, DSIP-like immunoreactive material was detected by immunocytochemistry.

    In plain wordsIn human pheochromocytoma tumor samples, the body's own DSIP-like material was found.

    Outcome
    Not applicableDSIP-LI in pheochromocytoma tumors
    Study

    humann = 9

    Human pheochromocytoma tumors, immunocytochemistry
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Delta sleep-inducing peptide (DSIP)-like immunoreactive (LI) material has been detected in nine different human pheochromocytoma tumors by immunocytochemistry.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueMechanism

    In primary human pheochromocytoma tumors, a variable number of tumor cells (25-75%) showed positive cytoplasmic labeling with DSIP antiserum.

    In plain wordsIn human pheochromocytoma tumor samples, between 25% and 75% of tumor cells carried the body's own DSIP-like material.

    Outcome
    Not applicableShare of primary tumor cells labelled by DSIP antiserum
    Study

    humann: not reported in source

    Human pheochromocytoma primary tumors, indirect immunofluorescence
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    In primary tumors subjected to indirect immunofluorescence a variable number of tumor cells (25-75%) showed positive cytoplasmic labeling after incubation with DSIP antiserum.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelIn vitro (cells)Other

    In cultured human pheochromocytoma cells, DSIP antiserum strongly labeled DSIP-like material in the cell bodies.

    In plain wordsIn cultured human tumor cells, the body's own DSIP-like material was found in the cell bodies.

    Outcome
    Not applicableDSIP-LI in cultured pheochromocytoma cells
    Study

    humann: not reported in source

    Cultured human pheochromocytoma cells
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Tumor cells grown in culture were strongly labeled by the DSIP antiserum with DSIP-LI concentrated to cell bodies.
    1 context sentence
    Summary · context
    Delta sleep-inducing peptide (DSIP)-like immunoreactive (LI) material has been detected in nine different human pheochromocytoma tumors by immunocytochemistry.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  4. 04LabEndogenous levelIn vitro (cells)Other

    In cultured human pheochromocytoma cells, DSIP-like immunoreactive material appeared in HPLC fractions of conditioned media, indicating secretion.

    In plain wordsIn cultured human tumor cells, the body's own DSIP-like material was released into the culture medium.

    Outcome
    Not applicableSecretion of DSIP-LI from cultured pheochromocytoma cells
    Study

    humann: not reported in source

    Cultured human pheochromocytoma cells, conditioned media
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    The presence of DSIP-LI in several HPLC fractions from conditioned culture media indicates secretion of DSIP-LI from cultured pheochromocytoma cells.
    1 context sentence
    Summary · context
    Delta sleep-inducing peptide (DSIP)-like immunoreactive (LI) material has been detected in nine different human pheochromocytoma tumors by immunocytochemistry.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  5. 05LabEndogenous levelIn vitro (cells)Mechanism

    In human pheochromocytoma cells, electron microscopic immunogold labeling showed DSIP-like material over the dense core of secretory granules.

    In plain wordsIn human tumor cells, the body's own DSIP-like material was found in the dense core of storage granules.

    Outcome
    Not applicableDSIP-LI in secretory granules of pheochromocytoma cells
    Study

    humann: not reported in source

    Human pheochromocytoma cells, electron microscopic immunocytochemistry
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Electron microscopic immunocytochemistry (immunogold labeling) of pheochromocytoma cells demonstrated DSIP-LI over the dense core of secretory granules.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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