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Study · Animal study (in vivo) · rabbit · 1991

3 results

[Sympathetic regulation of heart rhythm under the effect of delta sleep peptide and its deficiency].

Ul'ianinskiĭ LS, Zviaginstseva MA

Biulleten' eksperimental'noi biologii i meditsiny1 Jul 1991Cited by 1 (Europe PMC)

PMID1793863 (opens in a new tab)PepBankPUB-01793863
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rabbits, DSIP injection (60 nM/kg) lowered the positive chronotropic effect of stellate ganglion irritation.

    In plain wordsIn rabbits, DSIP lowered the heart rate rise caused by stimulating a sympathetic nerve ganglion.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreasePositive chronotropic effect during stellate ganglion irritation
    Study

    rabbitn = 16

    Outcome group
    Heart function · Cardiovascular
    Studied dose
    60 nM/kgAs given in this study (rabbit).

    Source sentences

    Summary
    It has been revealed, that peptide injection (60 nM/kg) produces lowered positive chronotropic effect and elongated response development during irritation of this ganglion.
    1 context sentence
    Summary · context
    In acute experiments on 16 rabbits we've studied effects of delta-sleep peptide and its deficiency on the irritation of the stellate ganglion.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rabbits, DSIP injection (60 nM/kg) lengthened the development of the response during stellate ganglion irritation.

    In plain wordsIn rabbits, DSIP slowed the development of the heart response to stimulating a sympathetic nerve ganglion.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseResponse development time during stellate ganglion irritation
    Study

    rabbitn = 16

    Outcome group
    Heart function · Cardiovascular
    Studied dose
    60 nM/kgAs given in this study (rabbit).

    Source sentences

    Summary
    It has been revealed, that peptide injection (60 nM/kg) produces lowered positive chronotropic effect and elongated response development during irritation of this ganglion.
    1 context sentence
    Summary · context
    In acute experiments on 16 rabbits we've studied effects of delta-sleep peptide and its deficiency on the irritation of the stellate ganglion.

Studies that did not test the peptide alone1

In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Delta sleep-inducing peptide (DSIP).

  1. 03AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Mechanism

    In rabbits, antiserum to DSIP (blocking natural DSIP) enhanced the sympathetic response during stellate ganglion irritation.

    In plain wordsIn rabbits, blocking the body's own DSIP with antiserum increased the heart response to nerve ganglion stimulation.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseSympathetic response after antiserum to DSIP
    Study

    rabbitn = 16

    Outcome group
    Heart function · Cardiovascular

    Source sentences

    Summary
    Administration of antiserum to delta-sleep peptide (T = 1:3000) causes opposite effect: enhances sympathetic response during irritation of the stellate ganglion.
    1 context sentence
    Summary · context
    In acute experiments on 16 rabbits we've studied effects of delta-sleep peptide and its deficiency on the irritation of the stellate ganglion.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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