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Study · Animal study (in vivo) · rat · 1991

4 results

Oxytocin-induced inhibition of feeding and drinking: no sexual dimorphism in rats.

Benelli A, Bertolini A, Arletti R

Neuropeptides1 Sept 1991Cited by 49 (Europe PMC)

PMID1791926 (opens in a new tab)DOI10.1016/0143-4179(91)90040-p (opens in a new tab)PepBankPUB-01791926
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In male and female rats, oxytocin inhibited feeding in a dose-dependent way after intracerebroventricular or intraperitoneal administration.

    In plain wordsIn rats, oxytocin reduced eating, and a higher dose reduced it more.

    Peptide
    Oxytocin
    Outcome
    DecreaseFeeding inhibition
    Study

    ratn: not reported in source

    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    Dose not stated · intracerebroventricular or intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Dose-dependent feeding and drinking inhibition was observed in either sex to about the same degree, both following intracerebroventricular or intraperitoneal administration.
    2 context sentences
    Summary · context
    The effect of oxytocin on feeding and drinking behaviours was compared in male and female rats.
    Summary · context
    The results were obtained whether in animals with free access to food and water or in schedule-fed animals fasting for 21h and in two different models of thirst (water deprivation for 16h, s.c. administration of hypertonic saline).
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In male and female rats, oxytocin inhibited drinking in a dose-dependent way after intracerebroventricular or intraperitoneal administration.

    In plain wordsIn rats, oxytocin reduced drinking, and a higher dose reduced it more.

    Peptide
    Oxytocin
    Outcome
    DecreaseDrinking inhibition
    Study

    ratn: not reported in source

    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    Dose not stated · intracerebroventricular or intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Dose-dependent feeding and drinking inhibition was observed in either sex to about the same degree, both following intracerebroventricular or intraperitoneal administration.
    2 context sentences
    Summary · context
    The effect of oxytocin on feeding and drinking behaviours was compared in male and female rats.
    Summary · context
    The results were obtained whether in animals with free access to food and water or in schedule-fed animals fasting for 21h and in two different models of thirst (water deprivation for 16h, s.c. administration of hypertonic saline).
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats, oxytocin-induced inhibition of feeding did not differ between males and females.

    In plain wordsIn rats, oxytocin reduced eating about the same in males and in females.

    Peptide
    Oxytocin
    Outcome
    No significant changeSex difference in feeding inhibition
    Study

    ratn: not reported in source

    Comparator
    Female versus male rats
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    Dose not stated · intracerebroventricular or intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    These data show that there is no sexual dimorphism in oxytocin-induced inhibition of feeding and drinking.
    3 context sentences
    Summary · context
    Dose-dependent feeding and drinking inhibition was observed in either sex to about the same degree, both following intracerebroventricular or intraperitoneal administration.
    Summary · context
    The effect of oxytocin on feeding and drinking behaviours was compared in male and female rats.
    Summary · context
    The results were obtained whether in animals with free access to food and water or in schedule-fed animals fasting for 21h and in two different models of thirst (water deprivation for 16h, s.c. administration of hypertonic saline).
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In rats, oxytocin-induced inhibition of drinking did not differ between males and females.

    In plain wordsIn rats, oxytocin reduced drinking about the same in males and in females.

    Peptide
    Oxytocin
    Outcome
    No significant changeSex difference in drinking inhibition
    Study

    ratn: not reported in source

    Comparator
    Female versus male rats
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    Dose not stated · intracerebroventricular or intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    These data show that there is no sexual dimorphism in oxytocin-induced inhibition of feeding and drinking.
    3 context sentences
    Summary · context
    Dose-dependent feeding and drinking inhibition was observed in either sex to about the same degree, both following intracerebroventricular or intraperitoneal administration.
    Summary · context
    The effect of oxytocin on feeding and drinking behaviours was compared in male and female rats.
    Summary · context
    The results were obtained whether in animals with free access to food and water or in schedule-fed animals fasting for 21h and in two different models of thirst (water deprivation for 16h, s.c. administration of hypertonic saline).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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