Enclomiphene does not alter the postpartum interval of suckled beef cows.

Schramm RD, Roberge S, Reeves JJ

Journal of animal science1 Oct 1991Cited by 3 (Europe PMC)

PMID1778825DOI10.2527/1991.69104112xPepBankPUB-01778825

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

8 results from studies that gave the peptide. No result from this study comes from people.

01AnimalAnimal study (in vivo)Efficacy outcome
In postpartum cows, days to first estrus did not differ between enclomiphene and controls.
In plain wordsIn cows after birth, time to first estrus did not differ between enclomiphene and controls.
Peptide
Enclomiphene
Outcome
No significant changeDays to first estrus
Study
cown = 52
postpartum Angus beef cows
Comparator
empty implants
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
three implants each containing 150 mg · silastic implants · d 20 to d 30 postpartumAs given in this study (cow).
Measurements
Days to first estrus
57 days
enclomiphene
Days to first estrus
56 days
control
Source sentences
Summary
Days to first estrus did not differ (P greater than .05) between enclomiphene-treated (57 +/- 6; n = 24) and control (56 +/- 4; n = 28) cows.
3 context sentences(design, population, supporting numbers)
Summary · context
Sixty postpartum Angus beef cows were stratified by age, body condition, and calving date and were randomly assigned to one of two treatment groups.
Summary · context
Group 1 cows (n = 24) received three silastic implants, each containing 150 mg of enclomiphene, on d 20 postpartum.
Summary · context
Group 2 cows (n = 28), received empty implants and served as controls.
Report a problemFND-0177882505
02AnimalAnimal study (in vivo)Mechanism
In postpartum cows, enclomiphene reduced total hypothalamic estradiol receptor concentrations versus controls.
In plain wordsIn cows after birth, enclomiphene reduced total hypothalamic estradiol receptors versus controls.
Peptide
Enclomiphene
Outcome
DecreaseTotal hypothalamic estradiol receptor concentration
Study
cown = 8
postpartum Angus beef cows
Comparator
empty implants
Outcome group
Receptor activity and mechanism · Endocrine and hormones
Studied dose
three implants each containing 150 mg · silastic implants · d 20 to d 30 postpartumAs given in this study (cow).
Source sentences
Summary
Concentrations of total and unoccupied hypothalamic and pituitary estradiol receptors were reduced by enclomiphene.
4 context sentences(design, population, supporting numbers)
Summary · context
Hypothalami and pituitaries were collected from four cows in each treatment group on d 30 postpartum and analyzed for concentrations of estradiol receptors.
Summary · context
Sixty postpartum Angus beef cows were stratified by age, body condition, and calving date and were randomly assigned to one of two treatment groups.
Summary · context
Group 1 cows (n = 24) received three silastic implants, each containing 150 mg of enclomiphene, on d 20 postpartum.
Summary · context
Group 2 cows (n = 28), received empty implants and served as controls.
Report a problemFND-0177882501
03AnimalAnimal study (in vivo)Mechanism
In postpartum cows, enclomiphene reduced total pituitary estradiol receptor concentrations versus controls.
In plain wordsIn cows after birth, enclomiphene reduced total pituitary estradiol receptors versus controls.
Peptide
Enclomiphene
Outcome
DecreaseTotal pituitary estradiol receptor concentration
Study
cown = 8
postpartum Angus beef cows
Comparator
empty implants
Outcome group
Receptor activity and mechanism · Endocrine and hormones
Studied dose
three implants each containing 150 mg · silastic implants · d 20 to d 30 postpartumAs given in this study (cow).
Source sentences
Summary
Concentrations of total and unoccupied hypothalamic and pituitary estradiol receptors were reduced by enclomiphene.
4 context sentences(design, population, supporting numbers)
Summary · context
Hypothalami and pituitaries were collected from four cows in each treatment group on d 30 postpartum and analyzed for concentrations of estradiol receptors.
Summary · context
Sixty postpartum Angus beef cows were stratified by age, body condition, and calving date and were randomly assigned to one of two treatment groups.
Summary · context
Group 1 cows (n = 24) received three silastic implants, each containing 150 mg of enclomiphene, on d 20 postpartum.
Summary · context
Group 2 cows (n = 28), received empty implants and served as controls.
Report a problemFND-0177882502
04AnimalAnimal study (in vivo)Mechanism
In postpartum cows, enclomiphene reduced unoccupied hypothalamic estradiol receptor concentrations versus controls.
In plain wordsIn cows after birth, enclomiphene reduced unoccupied hypothalamic estradiol receptors versus controls.
Peptide
Enclomiphene
Outcome
DecreaseUnoccupied hypothalamic estradiol receptor concentration
Study
cown = 8
postpartum Angus beef cows
Comparator
empty implants
Outcome group
Receptor activity and mechanism · Endocrine and hormones
Studied dose
three implants each containing 150 mg · silastic implants · d 20 to d 30 postpartumAs given in this study (cow).
Source sentences
Summary
Concentrations of total and unoccupied hypothalamic and pituitary estradiol receptors were reduced by enclomiphene.
4 context sentences(design, population, supporting numbers)
Summary · context
Hypothalami and pituitaries were collected from four cows in each treatment group on d 30 postpartum and analyzed for concentrations of estradiol receptors.
Summary · context
Group 1 cows (n = 24) received three silastic implants, each containing 150 mg of enclomiphene, on d 20 postpartum.
Summary · context
Implants were removed on d 30 postpartum.
Summary · context
Group 2 cows (n = 28), received empty implants and served as controls.
Report a problemFND-0177882507
05AnimalAnimal study (in vivo)Mechanism
In postpartum cows, enclomiphene reduced unoccupied pituitary estradiol receptor concentrations versus controls.
In plain wordsIn cows after birth, enclomiphene reduced unoccupied pituitary estradiol receptors versus controls.
Peptide
Enclomiphene
Outcome
DecreaseUnoccupied pituitary estradiol receptor concentration
Study
cown = 8
postpartum Angus beef cows
Comparator
empty implants
Outcome group
Receptor activity and mechanism · Endocrine and hormones
Studied dose
three implants each containing 150 mg · silastic implants · d 20 to d 30 postpartumAs given in this study (cow).
Source sentences
Summary
Concentrations of total and unoccupied hypothalamic and pituitary estradiol receptors were reduced by enclomiphene.
4 context sentences(design, population, supporting numbers)
Summary · context
Hypothalami and pituitaries were collected from four cows in each treatment group on d 30 postpartum and analyzed for concentrations of estradiol receptors.
Summary · context
Group 1 cows (n = 24) received three silastic implants, each containing 150 mg of enclomiphene, on d 20 postpartum.
Summary · context
Implants were removed on d 30 postpartum.
Summary · context
Group 2 cows (n = 28), received empty implants and served as controls.
Report a problemFND-0177882508
06AnimalAnimal study (in vivo)Efficacy outcome
In postpartum cows, enclomiphene did not significantly change LH concentrations versus controls on any sampling day.
In plain wordsIn cows after birth, enclomiphene did not significantly change LH levels versus controls on any sampling day.
Peptide
Enclomiphene
Outcome
No significant changeLH concentrations
Study
cown: not reported in source
postpartum Angus beef cows
Comparator
empty implants
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
three implants each containing 150 mg · silastic implants · d 20 to d 30 postpartumAs given in this study (cow).
Source sentences
Summary
Neither concentrations nor pulse frequencies of LH differed significantly between treatment groups on any of the 4 d.
3 context sentences(design, population, supporting numbers)
Summary · context
Sixty postpartum Angus beef cows were stratified by age, body condition, and calving date and were randomly assigned to one of two treatment groups.
Summary · context
Group 1 cows (n = 24) received three silastic implants, each containing 150 mg of enclomiphene, on d 20 postpartum.
Summary · context
Group 2 cows (n = 28), received empty implants and served as controls.
Report a problemFND-0177882503
07AnimalAnimal study (in vivo)Efficacy outcome
In postpartum cows, enclomiphene did not significantly change LH pulse frequency versus controls on any sampling day.
In plain wordsIn cows after birth, enclomiphene did not significantly change LH pulse frequency versus controls.
Peptide
Enclomiphene
Outcome
No significant changeLH pulse frequency
Study
cown: not reported in source
postpartum Angus beef cows
Comparator
empty implants
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
three implants each containing 150 mg · silastic implants · d 20 to d 30 postpartumAs given in this study (cow).
Source sentences
Summary
Neither concentrations nor pulse frequencies of LH differed significantly between treatment groups on any of the 4 d.
3 context sentences(design, population, supporting numbers)
Summary · context
Sixty postpartum Angus beef cows were stratified by age, body condition, and calving date and were randomly assigned to one of two treatment groups.
Summary · context
Group 1 cows (n = 24) received three silastic implants, each containing 150 mg of enclomiphene, on d 20 postpartum.
Summary · context
Group 2 cows (n = 28), received empty implants and served as controls.
Report a problemFND-0177882504
08AnimalAnimal study (in vivo)Efficacy outcome
In postpartum cows, days to conception did not differ between enclomiphene and controls.
In plain wordsIn cows after birth, time to conception did not differ between enclomiphene and controls.
Peptide
Enclomiphene
Outcome
No significant changeDays to conception
Study
cown: not reported in source
postpartum Angus beef cows
Comparator
empty implants
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
three implants each containing 150 mg · silastic implants · d 20 to d 30 postpartumAs given in this study (cow).
Measurements
Days to conception
81 days
enclomiphene
Days to conception
79 days
control
Source sentences
Summary
Days to conception did not differ between treated (81 +/- 9) and control (79 +/- 8) cows.
3 context sentences(design, population, supporting numbers)
Summary · context
Sixty postpartum Angus beef cows were stratified by age, body condition, and calving date and were randomly assigned to one of two treatment groups.
Summary · context
Group 1 cows (n = 24) received three silastic implants, each containing 150 mg of enclomiphene, on d 20 postpartum.
Summary · context
Group 2 cows (n = 28), received empty implants and served as controls.
Report a problemFND-0177882506

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
21 Oct 2026, 15:58 UTC
Study results updated
Version 1
21 Oct 2026, 12:50 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

MeSH terms

PepBank is a research reference. Talk to a doctor before you use any peptide.