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Study · Randomized controlled trial · n = 60 · 1991

3 results

[Mild forms of multi-infarct dementia: effectiveness of cerebrolysin].

Vereshchagin NV, Nekrasova EM, Lebedeva NV, Suslina ZA, Solov'ev OI, Piradov MA, Altunina MN

Sovetskaia meditsina1 Jan 1991Cited by 6 (Europe PMC)

PMID1767322 (opens in a new tab)PepBankPUB-01767322

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In patients with mild multi-infarct dementia, cerebrolysin significantly improved memory.

    In plain wordsIn patients with mild multi-infarct dementia, cerebrolysin improved memory.

    Outcome
    IncreaseMemory
    Study

    n = 60

    Comparator
    Placebo (same volume of 0.85% NaCl solution)
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    15 ml daily (10 ml in the morning and 5 ml in the evening) · intravenous · 28 daysAs given in this study (human).

    Source sentences

    Summary
    The study found a significant improvement of the memory (p-0.01), abstract thinking and time of reaction in the patients on cerebrolysin, confirmed also by the EEG-mapping.
    3 context sentences
    Summary · context
    The randomized double-blind placebo-controlled study of the effectiveness of cerebrolysin in a mild form of multi-infarct dementia was carried out.
    Summary · context
    Sixty patients were divided in two equal groups differing significantly at the beginning of the study by none of the compared parameters.
    Summary · context
    They received for 28 days daily drop intravenous doses of cerebrolysin (15 ml of the drug in 200 ml of a 0.85% NaCl solution: 10 ml in the morning and 5 ml in the evening) or placebo in the same amount of the solution.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In patients with mild multi-infarct dementia, cerebrolysin significantly improved abstract thinking.

    In plain wordsIn patients with mild multi-infarct dementia, cerebrolysin improved abstract thinking.

    Outcome
    IncreaseAbstract thinking
    Study

    n = 60

    Comparator
    Placebo (same volume of 0.85% NaCl solution)
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    15 ml daily (10 ml in the morning and 5 ml in the evening) · intravenous · 28 daysAs given in this study (human).

    Source sentences

    Summary
    The study found a significant improvement of the memory (p-0.01), abstract thinking and time of reaction in the patients on cerebrolysin, confirmed also by the EEG-mapping.
    3 context sentences
    Summary · context
    The randomized double-blind placebo-controlled study of the effectiveness of cerebrolysin in a mild form of multi-infarct dementia was carried out.
    Summary · context
    Sixty patients were divided in two equal groups differing significantly at the beginning of the study by none of the compared parameters.
    Summary · context
    They received for 28 days daily drop intravenous doses of cerebrolysin (15 ml of the drug in 200 ml of a 0.85% NaCl solution: 10 ml in the morning and 5 ml in the evening) or placebo in the same amount of the solution.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In patients with mild multi-infarct dementia, cerebrolysin significantly improved reaction time.

    In plain wordsIn patients with mild multi-infarct dementia, cerebrolysin improved reaction time.

    Outcome
    DecreaseReaction time
    Study

    n = 60

    Comparator
    Placebo (same volume of 0.85% NaCl solution)
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    15 ml daily (10 ml in the morning and 5 ml in the evening) · intravenous · 28 daysAs given in this study (human).

    Source sentences

    Summary
    The study found a significant improvement of the memory (p-0.01), abstract thinking and time of reaction in the patients on cerebrolysin, confirmed also by the EEG-mapping.
    3 context sentences
    Summary · context
    The randomized double-blind placebo-controlled study of the effectiveness of cerebrolysin in a mild form of multi-infarct dementia was carried out.
    Summary · context
    Sixty patients were divided in two equal groups differing significantly at the beginning of the study by none of the compared parameters.
    Summary · context
    They received for 28 days daily drop intravenous doses of cerebrolysin (15 ml of the drug in 200 ml of a 0.85% NaCl solution: 10 ml in the morning and 5 ml in the evening) or placebo in the same amount of the solution.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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