Skip to content

Study · Animal study (in vivo) · mouse · 1990

6 results

Effects of repeated administrations of facteur thymique sérique (FTS) on biochemical changes related to aging in senescence-accelerated mouse (SAM).

Zhao XH, Awaya A, Kobayashi H, Ohnuki T, Tokumitsu Y, Nomura Y

Japanese journal of pharmacology1 Jul 1990Cited by 12 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In SAM-P/8 mice, FTS enhanced kidney Mn-SOD activity.

    In plain wordsIn SAM-P/8 mice, FTS increased kidney Mn-SOD activity.

    Outcome
    IncreaseKidney Mn-SOD activity
    Study

    mousen: not reported in source

    Senescence-accelerated mice aged 9-10 months
    Outcome group
    Aging markers · Kidney and urinary
    Studied dose
    Dose not stated

    Source sentences

    Summary
    FTS enhanced the activity of Mn-SOD and Cu,Zn-SOD in the kidney of SAM-P/8 and Cu,Zn-SOD activity in the brain of both SAM-P/8 and SAM-R/1.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In SAM-P/8 mice, FTS enhanced kidney Cu,Zn-SOD activity.

    In plain wordsIn SAM-P/8 mice, FTS increased kidney Cu,Zn-SOD activity.

    Outcome
    IncreaseKidney Cu,Zn-SOD activity
    Study

    mousen: not reported in source

    Senescence-accelerated mice aged 9-10 months
    Outcome group
    Aging markers · Kidney and urinary
    Studied dose
    Dose not stated

    Source sentences

    Summary
    FTS enhanced the activity of Mn-SOD and Cu,Zn-SOD in the kidney of SAM-P/8 and Cu,Zn-SOD activity in the brain of both SAM-P/8 and SAM-R/1.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In SAM-P/8 and SAM-R/1 mice, FTS enhanced brain Cu,Zn-SOD activity.

    In plain wordsIn SAM-P/8 and SAM-R/1 mice, FTS increased brain Cu,Zn-SOD activity.

    Outcome
    IncreaseBrain Cu,Zn-SOD activity
    Study

    mousen: not reported in source

    Senescence-accelerated mice aged 9-10 months
    Outcome group
    Aging markers · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    FTS enhanced the activity of Mn-SOD and Cu,Zn-SOD in the kidney of SAM-P/8 and Cu,Zn-SOD activity in the brain of both SAM-P/8 and SAM-R/1.
  4. 04AnimalAnimal study (in vivo)Mechanism

    In SAM-P/8 mice, FTS decreased liver MAO-B activity.

    In plain wordsIn SAM-P/8 mice, FTS decreased liver MAO-B activity.

    Outcome
    DecreaseLiver MAO-B activity
    Study

    mousen: not reported in source

    Senescence-accelerated mice aged 9-10 months
    Outcome group
    Aging markers · Liver
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It decreased the activity of MAO-B in the liver and the contents of malondialdehyde (MDA) in the brain and kidney of SAM-P/8.
  5. 05AnimalAnimal study (in vivo)Mechanism

    In SAM-P/8 mice, FTS decreased brain malondialdehyde content.

    In plain wordsIn SAM-P/8 mice, FTS decreased brain malondialdehyde content.

    Outcome
    DecreaseBrain MDA content
    Study

    mousen: not reported in source

    Senescence-accelerated mice aged 9-10 months
    Outcome group
    Aging markers · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It decreased the activity of MAO-B in the liver and the contents of malondialdehyde (MDA) in the brain and kidney of SAM-P/8.
  6. 06AnimalAnimal study (in vivo)Mechanism

    In SAM-P/8 mice, FTS decreased kidney malondialdehyde content.

    In plain wordsIn SAM-P/8 mice, FTS decreased kidney malondialdehyde content.

    Outcome
    DecreaseKidney MDA content
    Study

    mousen: not reported in source

    Senescence-accelerated mice aged 9-10 months
    Outcome group
    Aging markers · Kidney and urinary
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It decreased the activity of MAO-B in the liver and the contents of malondialdehyde (MDA) in the brain and kidney of SAM-P/8.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.